[HTML][HTML] Psychomotor slowing in schizophrenia: implications for endophenotype and biomarker development

KJ Osborne, S Walther, SA Shankman… - Biomarkers in …, 2020 - Elsevier
Motor abnormalities (eg, dyskinesia, psychomotor slowing, neurological soft signs) are core
features of schizophrenia that occur independent of drug treatment and are associated with …

Differences in resting-state functional magnetic resonance imaging functional network connectivity between schizophrenia and psychotic bipolar probands and their …

SA Meda, A Gill, MC Stevens, RP Lorenzoni… - Biological …, 2012 - Elsevier
BACKGROUND: Schizophrenia and bipolar disorder share overlapping symptoms and
genetic etiology. Functional brain dysconnectivity is seen in both disorders. METHODS: We …

Aberrant salience network (bilateral insula and anterior cingulate cortex) connectivity during information processing in schizophrenia

TP White, V Joseph, ST Francis, PF Liddle - Schizophrenia research, 2010 - Elsevier
A salience network, comprising bilateral insula and anterior cingulate cortex (ACC), is
thought to play a role in recruiting relevant brain regions for the processing of sensory …

Working memory genetics in schizophrenia and related disorders: an RDoC perspective

E Schwarz, H Tost… - American Journal of …, 2016 - Wiley Online Library
Improved classification of mental disorders through neurobiological measures will require a
set of traits that map to transdiagnostic subgroups of patients and align with heritable, core …

Dysregulation of working memory and default‐mode networks in schizophrenia using independent component analysis, an fBIRN and MCIC study

DI Kim, DS Manoach, DH Mathalon… - Human brain …, 2009 - Wiley Online Library
Deficits in working memory (WM) are a consistent neurocognitive marker for schizophrenia.
Previous studies have suggested that WM is the product of coordinated activity in distributed …

Correspondence between fMRI and SNP data by group sparse canonical correlation analysis

D Lin, VD Calhoun, YP Wang - Medical image analysis, 2014 - Elsevier
Both genetic variants and brain region abnormalities are recognized as important factors for
complex diseases (eg, schizophrenia). In this paper, we investigated the correspondence …

Application of deep canonically correlated sparse autoencoder for the classification of schizophrenia

G Li, D Han, C Wang, W Hu, VD Calhoun… - Computer methods and …, 2020 - Elsevier
Background and objective Imaging genetics has been widely used to help diagnose and
treat mental illness, eg, schizophrenia, by combining magnetic resonance imaging of the …

Fronto-striatal dysfunction during reward processing in unaffected siblings of schizophrenia patients

M de Leeuw, RS Kahn, M Vink - Schizophrenia bulletin, 2015 - academic.oup.com
Schizophrenia is a psychiatric disorder that is associated with impaired functioning of the
fronto-striatal network, in particular during reward processing. However, it is unclear whether …

Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia

Z Kikinis, JH Fallon, M Niznikiewicz, P Nestor… - Schizophrenia …, 2010 - Elsevier
The dorsolateral prefrontal cortex (DLPFC) is a brain region that has figured prominently in
studies of schizophrenia and working memory, yet the exact neuroanatomical localization of …

[HTML][HTML] Dysconnectivity of neurocognitive networks at rest in very-preterm born adults

TP White, I Symington, NP Castellanos, PJ Brittain… - NeuroImage: Clinical, 2014 - Elsevier
Advances in neonatal medicine have resulted in a larger proportion of preterm-born
individuals reaching adulthood. Their increased liability to psychiatric illness and …