RNA granules are ubiquitous. Composed of RNA-binding proteins and RNAs, they provide
functional compartmentalization within cells. They are inextricably linked with RNA biology …

Many viruses carry more than one segment of nucleic acid into the virion particle, but
retroviruses are the only known group of viruses that contain two identical (or nearly …

The c-kit gene encodes a receptor tyrosine kinase, whose engagement by its ligand triggers
signals leading to cell proliferation. c-kit activity is elevated in gastrointestinal stromal tumors …

The diploid genome of all retroviruses is made of two homologous copies of RNA intimately
associated near their 5'end, in a region called the dimer linkage structure. Dimerization of …

Repeat tracts of guanine bases found in DNA and RNA can form tetraplex structures in the
presence of a variety of monovalent cations. Evidence suggests that guanine tetraplexes …

The selective encapsidation of retroviral RNA requires sequences in the Gag protein, as well
as a cis-acting RNA packaging signal (psi site) near the 5'end of the genomic transcript. Gag …

One of the hallmarks of HIV infection is the rapid development of a genetically complex
population (quasispecies) from an initially limited number of infectious particles. Genetic …

RNA-RNA interactions govern a number of biological processes. Several RNAs, including
natural sense and antisense RNAs, interact by means of a two-step mechanism: recognition …

Retroviruses are a family of widespread small animal viruses about 110 nm in diameter,
composed of an inner core surrounded by an outer envelope formed of a lipid bilayer of …

RNA Packaging Page 1 RNA Packaging R. BERKOWITZ 1, J. FISHER2, and SP GOFF2
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 2 Packaging …