Coronaviruses are large, enveloped RNA viruses of both medical and veterinary
importance. Interest in this viral family has intensified in the past few years as a result of the …

Coronaviruses are a family of enveloped, single-stranded, positive-strand RNA viruses
classified within the Nidovirales order. This coronavirus family consists of pathogens of …

Publisher Summary This chapter discusses the manipulation of clones of coronavirus and of
complementary DNAs (cDNAs) of defective-interfering (DI) RNAs to study coronavirus RNA …

Several viruses infect the mammalian central nervous system (CNS), some with devastating
consequences, others resulting in chronic or persistent infections associated with little or no …

Neutralizing monoclonal antibodies directed against five antigenic sites on the spike (S) S1
glycopolypeptide of avian infectious bronchitis virus (IBV) were used to select neutralization …

Coronaviruses (CoVs) are common human and animal pathogens that can transmit
zoonotically and cause severe respiratory disease syndromes. CoV infection requires spike …

We describe the isolation and characterization of a novel Betacoronavirus subgroup A
coronavirus, rabbit coronavirus HKU14 (RbCoV HKU14), from domestic rabbits. The virus …

Coronaviruses are frequently claimed to have a characteristic morphology, including the
possession of a “club-shaped” surface projection or spike (S) glycoprotein. However, in …

The spike glycoprotein (S) of coronavirus, the major target for virus-neutralizing antibodies,
is assumed to mediate the attachment of virions to the host cell. A 26-kilodalton fragment …

Previous results suggested that, after intranasal inoculation, mouse hepatitis virus (MHV), a
neurotropic coronavirus, entered the central nervous system (CNS) via the olfactory and …