5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas

K Mahmoudi, KL Garvey, A Bouras, G Cramer… - Journal of neuro …, 2019 - Springer
Introduction Photodynamic therapy (PDT) is a two-step treatment involving the
administration of a photosensitive agent followed by its activation at a specific light …

Current standards of care in glioblastoma therapy

C Fernandes, A Costa, L Osório, RC Lago… - Exon …, 2017 - exonpublications.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

Advances in brain tumor surgery for glioblastoma in adults

M Lara-Velazquez, R Al-Kharboosh, S Jeanneret… - Brain sciences, 2017 - mdpi.com
Glioblastoma (GBM) is the most common primary intracranial neoplasia, and is
characterized by its extremely poor prognosis. Despite maximum surgery, chemotherapy …

Fluorescence-guided surgery: a review on timing and use in brain tumor surgery

AJ Schupper, M Rao, N Mohammadi, R Baron… - Frontiers in …, 2021 - frontiersin.org
Fluorescence-guided surgery (FGS) allows surgeons to have improved visualization of
tumor tissue in the operating room, enabling maximal safe resection of malignant brain …

Perspective review of what is needed for molecular-specific fluorescence-guided surgery

BW Pogue, EL Rosenthal, S Achilefu… - … of biomedical optics, 2018 - spiedigitallibrary.org
Molecular image-guided surgery has the potential for translating the tools of molecular
pathology to real-time guidance in surgery. As a whole, there are incredibly positive …

Explorations into the Effect of meso‐Substituents in Tricarbocyanine Dyes: A Path to Diverse Biomolecular Probes and Materials

RM Exner, F Cortezon‐Tamarit… - Angewandte Chemie …, 2021 - Wiley Online Library
Polymethine cyanine dyes have been widely recognized as promising chemical tools for a
range of life science and biomedical applications, such as fluorescent staining of DNA and …

Diagnosis and management of glioblastoma: A comprehensive perspective

V Gilard, A Tebani, I Dabaj, A Laquerrière… - Journal of personalized …, 2021 - mdpi.com
Glioblastoma is the most common malignant brain tumor in adults. The current management
relies on surgical resection and adjuvant radiotherapy and chemotherapy. Despite …

Turning on the light for brain tumor surgery: a 5-aminolevulinic acid story

DJ McCracken, AJ Schupper, N Lakomkin… - Neuro …, 2022 - academic.oup.com
To aid surgeons in more complete and safe resection of brain tumors, adjuvant technologies
have been developed to improve visualization of target tissue. Fluorescence-guided surgery …

Effect of 5-aminolevulinic acid and sodium fluorescein on the extent of resection in high-grade gliomas and brain metastasis

LC Ahrens, MG Krabbenhøft, RW Hansen, N Mikic… - Cancers, 2022 - mdpi.com
Simple Summary Complete surgical removal of high-grade gliomas (HGG) is known to
increase the overall survival and progression-free survival. Several studies have shown that …

Conjugated polymers as nanoparticle probes for fluorescence and photoacoustic imaging

TF Abelha, CA Dreiss, MA Green… - Journal of materials …, 2020 - pubs.rsc.org
Bioimaging enables the visualisation of biological processes at the microscopic and
macroscopic levels, finding applications from cellular tracking to whole body scanning for …