Paraoxonase 1 and homocysteine metabolism

J Perła-Kaján, H Jakubowski - Amino acids, 2012 - Springer
Abstract Paraoxonase 1 (PON1), a component of high-density lipoprotein (HDL), is a
calcium-dependent multifunctional enzyme that connects metabolisms of lipoproteins and …

Cardiovascular biomarkers in chronic kidney disease: state of current research and clinical applicability

L D'Marco, A Bellasi, P Raggi - Disease markers, 2015 - Wiley Online Library
The high incidence of cardiovascular events in chronic kidney disease (CKD) warrants an
accurate evaluation of risk aimed at reducing the burden of disease and its consequences …

Association of chemerin with oxidative stress, inflammation and classical adipokines in non‐diabetic obese patients

P Fülöp, I Seres, H Lőrincz, M Harangi… - Journal of cellular …, 2014 - Wiley Online Library
The prevalence of obesity has been increasing worldwide. Chemerin is a recently
discovered adipokine secreted by the enlarged adipose tissue with diverse biological effects …

Atherogenesis: hyperhomocysteinemia interactions with LDL, macrophage function, paraoxonase 1, and exercise

I Chernyavskiy, S Veeranki, U Sen… - Annals of the new York …, 2016 - Wiley Online Library
Despite great strides in understanding the atherogenesis process, the mechanisms are not
entirely known. In addition to diet, cigarette smoking, genetic predisposition, and …

The effect of pomegranate consumption on cardiovascular risk factors in hemodialysis patients: a systematic review of clinical trials

G Baghdadi, F Shidfar, A Dehnad - Phytotherapy Research, 2023 - Wiley Online Library
Patients undergoing maintenance dialysis have a significantly higher incidence of
cardiovascular disease (CVD) compared with the general population. CVD is the most …

Cardioprotective role for paraoxonase-1 in chronic kidney disease

P Dube, FK Khalaf, A DeRiso, CJ Mohammed… - Biomedicines, 2022 - mdpi.com
Paraoxonase-1 (PON-1) is a hydrolytic enzyme associated with HDL, contributing to its anti-
inflammatory, antioxidant, and anti-atherogenic properties. Deficiencies in PON-1 activity …

PON1 lactonase activity and its association with cardiovascular disease

FE Murillo-González, N Ponce-Ruiz… - Clinica Chimica …, 2020 - Elsevier
Abstract Background Paraoxonase 1 (PON1) is important in the development of
atherosclerosis, and it has become the subject of intensive research. Our aim was to …

Circulating lactonase activity but not protein level of PON-1 predicts adverse outcomes in subjects with chronic kidney disease

CJ Mohammed, Y Xie, PS Brewster, S Ghosh… - Journal of clinical …, 2019 - mdpi.com
The burden of cardiovascular disease and death in chronic kidney disease (CKD) outpaces
that of the other diseases and is not adequately described by traditional risk factors alone …

[HTML][HTML] Decreases in paraoxonase-1 activities promote a pro-inflammatory effect of lipids peroxidation products in non-smoking and smoking patients with acute …

G Marek, M Ściskalska, Z Grzebieniak… - International Journal of …, 2018 - ncbi.nlm.nih.gov
Aim: The study investigated the extent to which tobacco smoke exposure causes changes in
lipids biochemistry through measurement blood concentrations of: paraoxonase-1 (PON-1) …

Paraoxonase 1 activity and renal replacement therapy for chronic renal failure: a meta-analysis

J Watanabe, K Kotani, Y Iwazu, A Gugliucci - Journal of Clinical Medicine, 2023 - mdpi.com
Chronic renal failure (CRF) is associated with the development of cardiovascular disease
(CVD). Paraoxonase 1 (PON1), an antioxidant enzyme, shows cardioprotective properties …