Current and emerging Legionella diagnostics for laboratory and outbreak investigations

JW Mercante, JM Winchell - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Legionnaires' disease (LD) is an often severe and potentially fatal form of bacterial
pneumonia caused by an extensive list of Legionella species. These ubiquitous freshwater …

Molecular epidemiology, phylogeny and evolution of Legionella

A Khodr, E Kay, L Gomez-Valero, C Ginevra… - Infection, genetics and …, 2016 - Elsevier
Legionella are opportunistic pathogens that develop in aquatic environments where they
multiply in protozoa. When infected aerosols reach the human respiratory tract they may …

Guidelines for the validation and application of typing methods for use in bacterial epidemiology

A Van Belkum, PT Tassios, L Dijkshoorn… - Clinical Microbiology …, 2007 - Wiley Online Library
For bacterial typing to be useful, the development, validation and appropriate application of
typing methods must follow unified criteria. Over a decade ago, ESGEM, the ESCMID …

[图书][B] Legionella and the prevention of legionellosis

J Bartram - 2007 - books.google.com
Water is the major natural reservoir for legionellae, and the bacteria are found worldwide in
many different natural and artificial aquatic environments, such as cooling towers, water …

Consensus Sequence-Based Scheme for Epidemiological Typing of Clinical and Environmental Isolates of Legionella pneumophila

V Gaia, NK Fry, B Afshar, PC Lück… - Journal of clinical …, 2005 - Am Soc Microbiol
ABSTRACT A previously described sequence-based epidemiological typing method for
clinical and environmental isolates of Legionella pneumophila serogroup 1 was extended …

[HTML][HTML] Use of sequence-based typing and multiplex PCR to identify clonal lineages of outbreak strains of Acinetobacter baumannii

JF Turton, SN Gabriel, C Valderrey… - Clinical microbiology …, 2007 - Elsevier
ABSTRACT Representatives (n= 31) of outbreak strains of Acinetobacter baumannii from
five countries fell into three clear groups, designated Groups 1–3, based on their ompA …

A pilot study of rapid whole-genome sequencing for the investigation of a Legionella outbreak

S Reuter, TG Harrison, CU Köser, MJ Ellington… - BMJ open, 2013 - bmjopen.bmj.com
Objectives Epidemiological investigations of Legionnaires' disease outbreaks rely on the
rapid identification and typing of clinical and environmental Legionella isolates in order to …

High-throughput multilocus sequence typing: bringing molecular typing to the next level

SA Boers, WA Van der Reijden, R Jansen - PloS one, 2012 - journals.plos.org
Multilocus sequence typing (MLST) is a widely used system for typing microorganisms by
sequence analysis of housekeeping genes. The main advantage of MLST in comparison to …

Prevalence of sequence types among clinical and environmental isolates of Legionella pneumophila serogroup 1 in the United States from 1982 to 2012

NA Kozak-Muiznieks, CE Lucas, E Brown… - Journal of clinical …, 2014 - Am Soc Microbiol
Since the establishment of sequence-based typing as the gold standard for DNA-based
typing of Legionella pneumophila, the Legionella laboratory at the Centers for Disease …

Legionella pneumophila strain associated with the first evidence of person-to-person transmission of Legionnaires' disease: a unique mosaic genetic backbone

V Borges, A Nunes, DA Sampaio, L Vieira… - Scientific reports, 2016 - nature.com
A first strong evidence of person-to-person transmission of Legionnaires' Disease (LD) was
recently reported. Here, we characterize the genetic backbone of this case-related …