The effect of the hypoxic tumor microenvironment (TME) on the effectiveness of cancer
treatments has received widespread attention. It is crucial to investigate the mechanisms by …

Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …

Background Validation of new biomarkers of Alzheimer disease (AD) is crucial for the
successful development and implementation of treatment strategies. Additional to traditional …

Simple Summary The expression of the cysteine–glutamate cotransporter, system xc−, is
increased in cancer cells across many cancer types. Imaging system xc− provides new …

Molecular imaging is the visual representation of biological processes that take place at the
cellular or molecular level in living organisms. To date, molecular imaging plays an …

This article first discusses many of the most prominent PET imaging agents in late preclinical
and early clinical development in oncology. These agents are intended to take advantage of …

Background 18F-fluorodeoxyglucose (FDG) PET/CT is recommended for evaluation of
intermediate-risk indeterminate pulmonary nodules (IPNs). While highly sensitive, the …

Ferroptosis is a distinct form of regulated cell death that is predominantly driven by the build-
up of intracellular iron and lipid peroxides. Ferroptosis suppression is widely accepted to …

Both cancer and fibrosis are diseases involving dysregulation of cell signaling pathways
resulting in an altered cellular microenvironment which ultimately leads to progression of the …

Simple Summary This clinical study explored the use of the positron emission tomography
radiotracer,[18F] FSPG, for cancer imaging.[18F] FSPG measures a process involved in …