Non-coding RNA in the wiring and remodeling of neural circuits

M Soutschek, G Schratt - Neuron, 2023 - cell.com
The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …

MEG3: an oncogenic long non-coding RNA in different cancers

A Al-Rugeebah, M Alanazi, NR Parine - Pathology & Oncology Research, 2019 - Springer
Long noncoding RNAs (lncRNAs) have recently considered as central regulators in diverse
biological processes and emerged as vital players controlling tumorigenesis. Several …

[HTML][HTML] Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing

SK Leung, AR Jeffries, I Castanho, BT Jordan, K Moore… - Cell reports, 2021 - cell.com
Alternative splicing is a post-transcriptional regulatory mechanism producing distinct mRNA
molecules from a single pre-mRNA with a prominent role in the development and function of …

Dimension-agnostic and granularity-based spatially variable gene identification using BSP

J Wang, J Li, ST Kramer, L Su, Y Chang, C Xu… - Nature …, 2023 - nature.com
Identifying spatially variable genes (SVGs) is critical in linking molecular cell functions with
tissue phenotypes. Spatially resolved transcriptomics captures cellular-level gene …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Besides pathology: long non-coding RNA in cell and tissue homeostasis

A Salviano-Silva, SC Lobo-Alves, RC Almeida… - Non-coding RNA, 2018 - mdpi.com
A significant proportion of mammalian genomes corresponds to genes that transcribe long
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …

Fear extinction is regulated by the activity of long noncoding RNAs at the synapse

WS Liau, Q Zhao, A Bademosi, RS Gormal… - Nature …, 2023 - nature.com
Long noncoding RNAs (lncRNAs) represent a multidimensional class of regulatory
molecules that are involved in many aspects of brain function. Emerging evidence indicates …

RNA from trained Aplysia can induce an epigenetic engram for long-term sensitization in untrained Aplysia

A Bédécarrats, S Chen, K Pearce, D Cai, DL Glanzman - Eneuro, 2018 - eneuro.org
The precise nature of the engram, the physical substrate of memory, remains uncertain.
Here, it is reported that RNA extracted from the central nervous system of Aplysia given long …

Role of long noncoding RNA MEG3/miR-378/GRB2 axis in neuronal autophagy and neurological functional impairment in ischemic stroke

HC Luo, TZ Yi, FG Huang, Y Wei, XP Luo… - Journal of Biological …, 2020 - ASBMB
Autophagy has been shown to maintain neural system homeostasis during stroke. However,
the molecular mechanisms underlying neuronal autophagy in ischemic stroke remain poorly …

Long non-coding RNAs in neuronal aging

D Pereira Fernandes, M Bitar, FMJ Jacobs, G Barry - Non-coding RNA, 2018 - mdpi.com
The expansion of long non-coding RNAs (lncRNAs) in organismal genomes has been
associated with the emergence of sophisticated regulatory networks that may have …