The role of glutathione in protecting against the severe inflammatory response triggered by COVID-19

F Silvagno, A Vernone, GP Pescarmona - Antioxidants, 2020 - mdpi.com
The novel COVID-19 pandemic is affecting the world's population differently: mostly in the
presence of conditions such as aging, diabetes and hypertension the virus triggers a lethal …

[HTML][HTML] Recent developments in the role of reactive oxygen species in allergic asthma

J Qu, Y Li, W Zhong, P Gao, C Hu - Journal of thoracic disease, 2017 - ncbi.nlm.nih.gov
Allergic asthma has a global prevalence, morbidity, and mortality. Many environmental
factors, such as pollutants and allergens, are highly relevant to allergic asthma. The most …

Glutathione-induced drought stress tolerance in mung bean: coordinated roles of the antioxidant defence and methylglyoxal detoxification systems

K Nahar, M Hasanuzzaman, MM Alam, M Fujita - AoB Plants, 2015 - academic.oup.com
Drought is considered one of the most acute environmental stresses presently affecting
agriculture. We studied the role of exogenous glutathione (GSH) in conferring drought stress …

Hydrogen sulfide exposure triggers chicken trachea inflammatory injury through oxidative stress-mediated FOS/IL8 signaling

M Chen, X Li, Q Shi, Z Zhang, S Xu - Journal of hazardous materials, 2019 - Elsevier
Hydrogen sulfide (H 2 S) is well known to cause irritation and damage to airway following
inhalation, but the mechanism by which H 2 S contributes to airway toxicity is unclear. In …

Molecular characterization of redox mechanisms in allergic asthma

L Jiang, PT Diaz, TM Best, JN Stimpfl, F He… - Annals of Allergy, Asthma …, 2014 - Elsevier
Objective To investigate the molecular redox mechanisms in allergic asthma and to examine
current studies of the disease to provide a basis for further investigation of oxidative stress in …

[HTML][HTML] Endoplasmic reticulum stress and glutathione therapeutics in chronic lung diseases

Y Janssen-Heininger, NL Reynaert, A van der Vliet… - Redox biology, 2020 - Elsevier
The lung is a unique organ, as it is constantly exposed to air and airborne pollutants
including oxidant gases such as highly reactive nitrogen dioxide and ozone, particulates …

Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases

SB Chia, EA Elko, R Aboushousha… - … of Physiology-Cell …, 2020 - journals.physiology.org
Glutathione is a major redox buffer, reaching millimolar concentrations within cells and high
micromolar concentrations in airways. While glutathione has been traditionally known as an …

Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and …

J Yoneda, S Nishikawa, S Kurihara - Bmc Cancer, 2021 - Springer
Background Chemotherapy is frequently used in cancer treatment; however, it may cause
adverse events, which must be managed. Reactive oxygen species (ROS) have been …

Vitamin D supplementation: oxidative stress modulation in a mouse model of ovalbumin-induced acute asthmatic airway inflammation

TI Adam-Bonci, EA Bonci, AE Pârvu… - International Journal of …, 2021 - mdpi.com
Asthma oxidative stress disturbances seem to enable supplementary proinflammatory
pathways, thus contributing to disease development and severity. The current study …

Therapy with resveratrol attenuates obesity-associated allergic airway inflammation in mice

DM Andre, MC Calixto, C Sollon, EC Alexandre… - International …, 2016 - Elsevier
Obesity and insulin resistance have been associated with deterioration in asthma outcomes.
High oxidative stress and deficient activation of AMP-activated protein kinase (AMPK) have …