Immunoassays in microfluidic systems

AHC Ng, U Uddayasankar, AR Wheeler - Analytical and bioanalytical …, 2010 - Springer
Immunoassays have greatly benefited from miniaturization in microfluidic systems. This
review, which summarizes developments in microfluidics-based immunoassays since 2000 …

Current development in microfluidic immunosensing chip

TG Henares, F Mizutani, H Hisamoto - Analytica chimica acta, 2008 - Elsevier
This review accounts for the current development in microfluidic immunosensing chips. The
basic knowledge of immunoassay in relation to its microfluidic material substrate, fluid …

Survey of the year 2007 commercial optical biosensor literature

RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2008 - Wiley Online Library
In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …

Mass transfer limitations of porous silicon-based biosensors for protein detection

S Arshavsky Graham, E Boyko, R Salama, E Segal - ACS sensors, 2020 - ACS Publications
Porous silicon (PSi) thin films have been widely studied for biosensing applications,
enabling label-free optical detection of numerous targets. The large surface area of these …

New advances in microfluidic flow cytometry

Y Gong, N Fan, X Yang, B Peng, H Jiang - Electrophoresis, 2019 - Wiley Online Library
In recent years, researchers are paying the increasing attention to the development of
portable microfluidic diagnostic devices including microfluidic flow cytometry for the point‐of …

Flow-through porous silicon membranes for real-time label-free biosensing

Y Zhao, G Gaur, ST Retterer, PE Laibinis… - Analytical …, 2016 - ACS Publications
A flow-through sensing platform based on open-ended porous silicon (PSi) microcavity
membranes that are compatible with integration in on-chip sensor arrays is demonstrated …

Flow-through vs flow-over: analysis of transport and binding in nanohole array plasmonic biosensors

C Escobedo, AG Brolo, R Gordon, D Sinton - Analytical chemistry, 2010 - ACS Publications
We quantify the efficacy of flow-through nanohole sensing, as compared to the established
flow-over format, through scaling analysis and numerical simulation. Nanohole arrays …

Shear‐rate‐dependent rheology effects on mass transport and surface reactions in biomicrofluidic devices

A Sadeghi, Y Amini, MH Saidi, H Yavari - AIChE Journal, 2015 - Wiley Online Library
Consideration is given to shear‐rate‐dependent rheology effects on mass transport in a
heterogeneous microreactor of rectangular cross section, utilizing both numerical and …

Microfluidic whole-blood immunoassays

H Jiang, X Weng, D Li - Microfluidics and nanofluidics, 2011 - Springer
Immunoassay is one of the most widely used biomedical diagnostic methods due to its
sensitivity and specificity. Microfluidic lab-on-a-chip technology has the advantages of …

Portable optical immunosensor for highly sensitive detection of microcystin-LR in water samples

F Long, M He, AN Zhu, HC Shi - Biosensors and Bioelectronics, 2009 - Elsevier
Fast and sensitive detection of microcystin-LR (MC-LR) was conducted with a portable trace
organic pollutant analyzer (TOPA) based on the principle of immunoassay and total internal …