Sleep—A brain-state serving systems memory consolidation
Although long-term memory consolidation is supported by sleep, it is unclear how it differs
from that during wakefulness. Our review, focusing on recent advances in the field, identifies …
from that during wakefulness. Our review, focusing on recent advances in the field, identifies …
The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit
The Drosophila brain contains a relatively simple circuit for forming Pavlovian associations,
yet it achieves many operations common across memory systems. Recent advances have …
yet it achieves many operations common across memory systems. Recent advances have …
[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …
deep brain regions, which are experimentally challenging to study. In insects, recurrent …
The connectome of the adult Drosophila mushroom body provides insights into function
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
[HTML][HTML] Re-examining the role of the dorsal fan-shaped body in promoting sleep in Drosophila
The needs fulfilled by sleep are unknown, though the effects of insufficient sleep are
manifold. To better understand how the need to sleep is sensed and discharged, much effort …
manifold. To better understand how the need to sleep is sensed and discharged, much effort …
Regulation of sleep by cholinergic neurons located outside the central brain in Drosophila
JD Jones, BL Holder, KR Eiken, A Vogt, AI Velarde… - PLoS …, 2023 - journals.plos.org
Sleep is a complex and plastic behavior regulated by multiple brain regions and influenced
by numerous internal and external stimuli. Thus, to fully uncover the function (s) of sleep …
by numerous internal and external stimuli. Thus, to fully uncover the function (s) of sleep …
[HTML][HTML] A paradoxical kind of sleep in Drosophila melanogaster
LAL Tainton-Heap, LC Kirszenblat, ET Notaras… - Current Biology, 2021 - cell.com
The dynamic nature of sleep in many animals suggests distinct stages that serve different
functions. Genetic sleep induction methods in animal models provide a powerful way to …
functions. Genetic sleep induction methods in animal models provide a powerful way to …
Developmental emergence of sleep rhythms enables long-term memory in Drosophila
AR Poe, L Zhu, M Szuperak, PD McClanahan… - Science …, 2023 - science.org
In adulthood, sleep-wake rhythms are one of the most prominent behaviors under circadian
control. However, during early life, sleep is spread across the 24-hour day. The mechanism …
control. However, during early life, sleep is spread across the 24-hour day. The mechanism …
Taste quality and hunger interactions in a feeding sensorimotor circuit
Taste detection and hunger state dynamically regulate the decision to initiate feeding. To
study how context-appropriate feeding decisions are generated, we combined synaptic …
study how context-appropriate feeding decisions are generated, we combined synaptic …
A neural circuit linking learning and sleep in Drosophila long-term memory
Animals retain some but not all experiences in long-term memory (LTM). Sleep supports
LTM retention across animal species. It is well established that learning experiences …
LTM retention across animal species. It is well established that learning experiences …