Malignant melanoma is the most aggressive form of skin cancer. Standard treatment options
include surgery, radiation therapy, systemic chemotherapy, targeted therapy, and …

Simple Summary While melanoma treatment has advanced and generally offers good
results, treatment resistance remains a major source of morbidity and mortality in the …

Tumor-associated macrophages (TAMs) promote tumor development and metastasis and
are categorized into M1-like macrophages, suppressing tumor cells, and M2-like …

Simple Summary Pancreatic cancer is an insidious disease, often diagnosed late in its
course when curative treatments are moot, with a 5-year median overall survival of~ 12 …

Patients with human papillomavirus-negative head and neck squamous cell carcinoma
(HPV-negative HNSCC) have worse outcomes than HPV-positive HNSCC. In our study, we …

Simple Summary Metastatic melanoma treatment has greatly changed in the last decade
due to the introduction of target therapies and immune checkpoint inhibitors. The …

Immunotherapy targeting program cell death protein 1 (PD-1) in addition to chemotherapy
has improved the survival of triple-negative breast cancer (TNBC) patients. However, the …

Simple Summary Hepatocellular carcinoma (HCC) is the most common type of liver cancer,
accounting for approximately 85–90% of all cases of liver cancer worldwide. The gut …

The skin and the gut are regularly colonized by a variety of microorganisms capable of
interacting with the immune system through their metabolites and influencing the balance …

Targeting the microbiome, microbiota-derived metabolites, and related pathways represents
a significant challenge in oncology. Microbiome analyses have confirmed the negative …