Despite being thirteen years since the installation of the first PET-MR system, the scanners
constitute a very small proportion of the total hybrid PET systems installed. This is in stark …

In this review, we will summarize the past and current state-of-the-art developments in
attenuation and scatter correction approaches for hybrid positron emission tomography …

Simple Summary Up to 70% of chemotherapy-treated patients experience problems with
memory and concentration, potentially caused by direct and indirect neurotoxicity, such as …

Abstract Rationale 11 C-UCB-J binds to synaptic vesicle glycoprotein 2A, a protein
ubiquitously expressed in presynaptic nerve terminals, and can therefore serve as in vivo …

Background and Objectives Synaptic damage has been proposed to play a major role in the
pathophysiology of Huntington disease (HD), but in vivo evidence in humans is lacking. We …

Abstract Purpose The P2X7 receptor (P2X7R) is an ATP-gated ion channel predominantly
expressed on activated microglia and is important in neurodegenerative diseases including …

Background Development of disease‐modifying treatments for Huntington's disease (HD)
could be aided by the use of imaging biomarkers of disease progression. Positron emission …

Preclinical and postmortem studies have suggested that regional synaptic density and
glucose consumption (CMRGlc) are strongly related. However, the relation between …

[18F] MK-6240 is a second-generation tau PET-tracer to quantify neurofibrillary tangles in-
vivo. However, individually variable levels of meningeal uptake induce spill-in-effects into …

Functional alterations after ischemic stroke have been described with Magnetic Resonance
Imaging (MRI) and perfusion Positron Emission Tomography (PET), but no data on in vivo …