Rapid changes of protein phosphorylation play a crucial role in the regulation of many
cellular processes. Being post-translationally modified, phosphoproteins are often present in …

Phosphorylation is a form of protein posttranslational modification (PTM) that regulates many
biological processes. Whereas phosphoproteomics is a scientific discipline that identifies …

AT cell receptor (TCR) mediates antigen-induced signaling through its associated CD3ε, δ,
γ, and ζ, but the contributions of different CD3 chains remain elusive. Using quantitative …

Regulated interactions between kinetochores and spindle microtubules are essential to
maintain genomic stability during chromosome segregation. The Aurora B kinase …

The subcellular localization of proteins is critical for their functions in eukaryotic cells and is
tightly correlated with protein modifications. Here, we comprehensively investigate the …

Hepatic glucose production (HGP) is crucial for glucose homeostasis, but the underlying
mechanisms have not been fully elucidated. Here, we show that a calcium-sensing enzyme …

Mitotic chromosome segregation requires that kinetochores attach to microtubule polymers
and harness microtubule dynamics to drive chromosome movement. In budding yeast, the …

The elucidation of protein post-translational modifications, such as phosphorylation, remains
a challenging analytical task for proteomic studies. Since many of the proteins targeted for …

Mass spectrometry is the tool of choice to investigate protein phosphorylation, which plays a
vital role in cell regulation and diseases such as cancer. However, low abundances of …

Simple Summary This review discusses current techniques used to study post-translational
protein modifications (PTMs) and their contribution to blood cancer research. Blood cancer …