Idiopathic REM sleep behaviour disorder and neurodegeneration—an update

B Högl, A Stefani, A Videnovic - Nature Reviews Neurology, 2018 - nature.com
So-called idiopathic rapid eye movement (REM) sleep behaviour disorder (RBD), formerly
seen as a rare parasomnia, is now recognized as the prodromal stage of an α …

Biomarkers for Parkinson's disease: how good are they?

T Li, W Le - Neuroscience bulletin, 2020 - Springer
Parkinson's disease (PD) is a complex neurodegenerative disorder with no cure in sight.
Clinical challenges of the disease include the inability to make a definitive diagnosis at the …

Dopamine transporter imaging deficit predicts early transition to synucleinopathy in idiopathic rapid eye movement sleep behavior disorder

A Iranzo, J Santamaría, F Valldeoriola… - Annals of …, 2017 - Wiley Online Library
Objective To determine the usefulness of dopamine transporter (DAT) imaging to identify
idiopathic rapid eye movement sleep behavior disorder (IRBD) patients at risk for short‐term …

Neuroimaging of Parkinson's disease: Expanding views

CP Weingarten, MH Sundman, P Hickey… - … & Biobehavioral Reviews, 2015 - Elsevier
Advances in molecular and structural and functional neuroimaging are rapidly expanding
the complexity of neurobiological understanding of Parkinson's disease (PD). This review …

Neural Control of REM Sleep and Motor Atonia: Current Perspectives

R Vetrivelan, SS Bandaru - Current neurology and neuroscience reports, 2023 - Springer
Abstract Purpose of Review Since the formal discovery of rapid eye movement (REM) sleep
in 1953, we have gained a vast amount of knowledge regarding the specific populations of …

[HTML][HTML] Neuroimaging in pre-motor Parkinson's disease

TR Barber, JC Klein, CE Mackay, MTM Hu - NeuroImage: Clinical, 2017 - Elsevier
The process of neurodegeneration in Parkinson's disease begins long before the onset of
clinical motor symptoms, resulting in substantial cell loss by the time a diagnosis can be …

Presynaptic dopaminergic neuroimaging in REM sleep behavior disorder: a systematic review and meta-analysis

M Bauckneht, A Chincarini, F De Carli, M Terzaghi… - Sleep medicine …, 2018 - Elsevier
The presence of polysomnography-confirmed REM sleep behavior disorder (RBD) is the
stronger risk factor for having prodromal Parkinson disease (PD), followed by abnormal …

Impact of sleep disorder as a risk factor for dementia in men and women

HJ Jee, W Shin, HJ Jung, B Kim… - Biomolecules & …, 2019 - pmc.ncbi.nlm.nih.gov
Sleep is an essential physiological process, especially for proper brain function through the
formation of new pathways and processing information and cognition. Therefore, when …

Movement disorders induced by psychiatric drugs that do not block dopamine receptors

JH Friedman - Parkinsonism & Related Disorders, 2020 - Elsevier
Most movement disorders in psychiatric patients are induced by neuroleptic antipsychotic
medications, all of which are dopamine D2 receptor blocking drugs. These include: acute …

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

I Kawakami, J Iga, S Takahashi, YT Lin… - Psychiatry and …, 2022 - Wiley Online Library
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more
likely to appear in SD than in early‐life depression, but it remains unclear whether the …