Chitosan nanocomposite for tissue engineering and regenerative medicine: a review

P Gupta, S Sharma, S Jabin, S Jadoun - International journal of biological …, 2024 - Elsevier
Regenerative medicine and tissue engineering have emerged as a multidisciplinary
promising field in the quest to address the limitations of traditional medical approaches. One …

[HTML][HTML] Mitochondrial metabolism: a new dimension of personalized oncology

B Behnam, F Taghizadeh-Hesary - Cancers, 2023 - mdpi.com
Simple Summary Cancer cells are dependent on normal cells for their survival and
functionality because they can use nanoscale tubes to steal the mitochondria from immune …

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

KS Allemailem, MA Alsahli, A Almatroudi… - Cancer …, 2022 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats‐associated protein
(CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust …

Functional materials for subcellular targeting strategies in cancer therapy: progress and prospects

Y Cheng, Z Qu, Q Jiang, T Xu, H Zheng, P Ye… - Advanced …, 2023 - Wiley Online Library
Neoadjuvant and adjuvant therapies have made significant progress in cancer treatment.
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …

[HTML][HTML] Oxidative damage to mitochondria enhanced by ionising radiation and gold nanoparticles in cancer cells

F Tabatabaie, R Franich, B Feltis, M Geso - International journal of …, 2022 - mdpi.com
Gold nanoparticles (AuNP) can increase the efficacy of radiation therapy by sensitising
tumor cells to radiation damage. When used in combination with radiation, AuNPs enhance …

[HTML][HTML] Recent advancements in mitochondria-targeted nanoparticle drug delivery for cancer therapy

J Xu, JG Shamul, EA Kwizera, X He - Nanomaterials, 2022 - mdpi.com
Mitochondria are critical subcellular organelles that produce most of the adenosine
triphosphate (ATP) as the energy source for most eukaryotic cells. Moreover, recent findings …

Novel approaches of dysregulating lysosome functions in cancer cells by specific drugs and its nanoformulations: a smart approach of modern therapeutics

KS Allemailem, A Almatroudi, F Alrumaihi… - International journal …, 2021 - Taylor & Francis
The smart strategy of cancer cells to bypass the caspase-dependent apoptotic pathway has
led to the discovery of novel anti-cancer approaches including the targeting of lysosomes …

[HTML][HTML] Delivery systems for mitochondrial gene therapy: a review

R Faria, P Boisguérin, Â Sousa, D Costa - Pharmaceutics, 2023 - mdpi.com
Mitochondria are membrane-bound cellular organelles of high relevance responsible for the
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …

Innovative approaches of engineering tumor-targeting bacteria with different therapeutic payloads to fight cancer: A smart strategy of disease management

KS Allemailem - International Journal of Nanomedicine, 2021 - Taylor & Francis
Conventional therapies for cancer eradication like surgery, radiotherapy, and chemotherapy,
even though most widely used, still suffer from some disappointing outcomes. The limitations …

[HTML][HTML] Polymeric nanoparticles for mitochondria targeting mediated robust cancer therapy

Y Sun, Q Yang, X Xia, X Li, W Ruan… - … in Bioengineering and …, 2021 - frontiersin.org
Despite all sorts of innovations in medical researches over the past decades, cancer
remains a major threat to human health. Mitochondria are essential organelles in eukaryotic …