Wiring and volume transmission: an overview of the dual modality for serotonin neurotransmission

G Gianni, M Pasqualetti - ACS Chemical Neuroscience, 2023 - ACS Publications
Serotonin is a neurotransmitter involved in the modulation of a multitude of physiological
and behavioral processes. In spite of the relatively reduced number of serotonin-producing …

Neuron–glial interactions: implications for plasticity, behavior, and cognition

M Rangel-Gomez, CM Alberini, B Deneen… - Journal of …, 2024 - jneurosci.org
The traditional view of glial cells as mere supportive tissue has shifted, due to advances in
technology and theoretical conceptualization, to include a diversity of other functions, such …

Disease-associated astrocyte epigenetic memory promotes CNS pathology

HG Lee, JM Rone, Z Li, CF Akl, SW Shin, JH Lee… - Nature, 2024 - nature.com
Disease-associated astrocyte subsets contribute to the pathology of neurologic diseases,
including multiple sclerosis and experimental autoimmune encephalomyelitis,,,,,,–(EAE), an …

Crym-positive striatal astrocytes gate perseverative behaviour

M Ollivier, JS Soto, KE Linker, SL Moye… - Nature, 2024 - nature.com
Astrocytes are heterogeneous glial cells of the central nervous system,–. However, the
physiological relevance of astrocyte diversity for neural circuits and behaviour remains …

Histone serotonylation regulates ependymoma tumorigenesis

HC Chen, P He, M McDonald, MR Williamson… - Nature, 2024 - nature.com
Bidirectional communication between tumours and neurons has emerged as a key facet of
the tumour microenvironment that drives malignancy,. Another hallmark feature of cancer is …

Learning-associated astrocyte ensembles regulate memory recall

MR Williamson, W Kwon, J Woo, Y Ko, E Maleki, K Yu… - Nature, 2024 - nature.com
The physical manifestations of memory formation and recall are fundamental questions that
remain unresolved. At the cellular level, ensembles of neurons called engrams are activated …

[HTML][HTML] Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome

JC Chan, N Alenina, AM Cunningham… - Journal of Molecular …, 2024 - Elsevier
Brain development requires appropriate regulation of serotonin (5-HT) signaling from
distinct tissue sources across embryogenesis. At the maternal-fetal interface, the placenta is …

Extracellular vesicles from mouse trophoblast cells: Effects on neural progenitor cells and potential participants in the placenta–brain axis

JA Kinkade, AS Seetharam, S Sachdev… - Biology of …, 2024 - academic.oup.com
The fetal brain of the mouse is thought to be dependent upon the placenta as a source of
serotonin (5-hydroxytryptamine; 5-HT) and other factors. How factors reach the developing …

Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing

A Gungor Aydin, A Lemenze, KM Bieszczad - Scientific reports, 2024 - nature.com
The mammalian cerebral cortex is composed of a rich diversity of cell types. Sensory cortical
cells are organized into networks that rely on their functional diversity to ultimately carry out …

Olfactory bulb astrocytes link social transmission of stress to cognitive adaptation in male mice

P Gómez-Sotres, U Skupio, T Dalla Tor… - Nature …, 2024 - nature.com
Emotions and behavior can be affected by social chemosignals from conspecifics. For
instance, olfactory signals from stressed individuals induce stress-like physiological and …