Behaviour of cytoplasmic organelles and cytoskeleton during oocyte maturation

L Mao, H Lou, Y Lou, N Wang, F Jin - Reproductive biomedicine online, 2014 - Elsevier
Assisted reproduction technology (ART) has become an attractive option for infertility
treatment and holds tremendous promise. However, at present, there is still room for …

Actin polymerization and depolymerization in developing vertebrates

Y Bai, F Zhao, T Wu, F Chen, X Pang - Frontiers in physiology, 2023 - frontiersin.org
Development is a complex process that occurs throughout the life cycle. F-actin, a major
component of the cytoskeleton, is essential for the morphogenesis of tissues and organs …

Impact of media supplements FGF2, LIF and IGF1 on the genome activity of porcine embryos produced in vitro

A Rosenbaum Bartkova, L Nemcova, F Strejcek… - Scientific Reports, 2024 - nature.com
In this article, we focused on the impact of precisely chemically modified FLI maturation
medium enriched with fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF) …

[HTML][HTML] Antimony exposure affects oocyte quality and early embryo development via excessive mitochondrial oxidation and dysfunction

X Wang, X Wu, W Ma, Q Wang, Y Chen, X Zhao… - … and Environmental Safety, 2024 - Elsevier
Antimony (Sb) is a metalloid, widely presents in the environment and associates with human
health. In this study, we aimed to decipher whether Sb exposure is harmful to female …

ROCK inhibition prevents early mouse embryo development

X Duan, KL Chen, Y Zhang, XS Cui, NH Kim… - Histochemistry and cell …, 2014 - Springer
ROCK is a Rho-GTPase effector that is important for actin assembly and is involved in
various cellular functions, including cell contraction, migration, motility, and tumor cell …

Involvement of LIMK1/2 in actin assembly during mouse embryo development

X Duan, HL Zhang, LL Wu, MY Liu, MH Pan, XH Ou… - Cell Cycle, 2018 - Taylor & Francis
ABSTRACT LIMKs (LIMK1 and LIMK2) are serine/threonine protein kinases that involve in
various cellular activities such as cell migration, morphogenesis and cytokinesis. However …

[HTML][HTML] LIMK1/2 are required for actin filament and cell junction assembly in porcine embryos developing in vitro

J Kwon, MJ Seong, X Piao, YJ Jo… - Asian-Australasian journal …, 2020 - ncbi.nlm.nih.gov
Objective This study was conducted to investigate the roles of LIM kinases (LIMK1 and
LIMK2) during porcine early embryo development. We checked the mRNA expression …

[HTML][HTML] Inhibition of Rho‑associated protein kinase increases the ratio of formation of blastocysts from single human blastomeres

S Huang, C Ding, Q Mai, Y Xu… - Molecular Medicine …, 2016 - spandidos-publications.com
Y‑27632 is a specific inhibitor of Rho‑associated protein kinases (ROCKs), which are
downstream effectors of Rho GTPase. The present study aimed to determine the effect of the …

Immunocytochemical localization of cytoplasmic and nuclear intermediate filaments in the bovine ovary during folliculogenesis

J Wendl, K Ebach, D Rodler… - Anatomia, Histologia …, 2012 - Wiley Online Library
The cellular cytoskeleton is composed of three fibrillar systems, namely actin microfilaments,
microtubules and intermediate filaments (IF s). It not only is a structural system, which …

Investigation of LAMTOR1 gene and protein expressions in germinal vesicle and metaphase II oocytes and embryos from 1-cell to blastocyst stage in a mouse model

E Gumus, I Sari, M Yilmaz, A Cetin - Gene Expression Patterns, 2018 - Elsevier
Highlights•LAMTOR1 expressed oocyte and different stages of preimplantation
embryos.•LAMTOR1 has a significant increased embryonic expression at 2-cell to morula …