Childhood acute lymphoblastic leukemia: progress through collaboration

CH Pui, JJ Yang, SP Hunger, R Pieters… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …

Philadelphia chromosome–like acute lymphoblastic leukemia

SK Tasian, ML Loh, SP Hunger - Blood, The Journal of the …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …

High frequency and poor outcome of Philadelphia chromosome–like acute lymphoblastic leukemia in adults

KG Roberts, Z Gu, D Payne-Turner… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a high-
risk subtype of childhood ALL characterized by kinase-activating alterations that are …

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults

N Jain, KG Roberts, E Jabbour, K Patel… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk
subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph …

Genomics in acute lymphoblastic leukaemia: insights and treatment implications

KG Roberts, CG Mullighan - Nature reviews Clinical oncology, 2015 - nature.com
Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …

[HTML][HTML] New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia

AV Moorman - Haematologica, 2016 - ncbi.nlm.nih.gov
Acute lymphoblastic leukemia (ALL) is a heterogeneous disease at the genetic level.
Chromosomal abnormalities are used as diagnostic, prognostic and predictive biomarkers to …

Outcomes of Children With BCR-ABL1–Like Acute Lymphoblastic Leukemia Treated With Risk-Directed Therapy Based on the Levels of Minimal Residual Disease

KG Roberts, D Pei, D Campana… - Journal of Clinical …, 2014 - ascopubs.org
Purpose BCR-ABL1–like acute lymphoblastic leukemia (ALL) is a recently identified B-cell
ALL (B-ALL) subtype with poor outcome that exhibits a gene expression profile similar to …

Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements

I Tanasi, I Ba, N Sirvent, T Braun… - Blood, The Journal …, 2019 - ashpublications.org
Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class
rearrangements | Blood | American Society of Hematology Skip to Main Content Advertisement …

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia

AV Moorman, A Enshaei, C Schwab… - Blood, The Journal …, 2014 - ashpublications.org
Recent genomic studies have provided a refined genetic map of acute lymphoblastic
leukemia (ALL) and increased the number of potential prognostic markers. Therefore, we …