Importance Interventions to reduce severe brain injury risk are the prime focus in neonatal
clinical trials. Objective To evaluate multiple perinatal interventions across clinical settings …

Mechanical ventilation is necessary and life saving in many neonates. Most complications
are inherent to this intervention and cannot be confused with iatrogenic errors in judgment or …

OBJECTIVE. The goal was to test the hypothesis that extremes of Paco2 during the first 4
days after birth are associated with severe intraventricular hemorrhage (grades 3 and 4) …

There is no consensus on the optimal pCO2 levels in the newborn. We reviewed the effects
of hypercapnia and hypocapnia and existing carbon dioxide thresholds in neonates. A …

Cerebrovascular lesions, mainly germinal matrix hemorrhage and ischemic injury to the
periventricular white matter, are major causes of adverse neurodevelopmental outcome in …

Background Tolerating higher partial pressure of carbon dioxide (pCO 2) in mechanically
ventilated, extremely low birthweight infants might reduce ventilator-induced lung injury and …

Since Northway's original description of BPD almost 45 years ago, the clinical presentation
of BPD has evolved into a disease process, which mostly involves extremely premature …

Background: Very preterm birth often results in the development of bronchopulmonary
dysplasia (BPD) with an inverse correlation of gestational age and birthweight. This very …

The current bronchopulmonary dysplasia (BPD) is seen in infants born extremely premature,
with less severe respiratory distress syndrome (RDS) and who received prenatal steroids …

Permissive hypercapnia: what to remember : Current Opinion in Anesthesiology Permissive
hypercapnia: what to remember : Current Opinion in Anesthesiology Log in or Register …