Cholesterol is an essential structural component of membranes that contributes to
membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the …

Cholesterol is required for maintenance of plasma membrane fluidity and integrity and for
many cellular functions. Cellular cholesterol can be obtained from lipoproteins in a selective …

The transmissible respiratory disease COVID-19, caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected millions of people worldwide since its …

Scavenger receptor class B type I (SR-BI), is a physiologically relevant HDL receptor that
mediates selective uptake of lipoprotein (HDL)-derived cholesteryl ester (CE) in vitro and in …

Abstract Purpose of Review The binding of high-density lipoprotein (HDL) to its primary
receptor, scavenger receptor class B type 1 (SR-B1), is critical for lowering plasma …

In rodents, SR-BI has been firmly established as a physiologically relevant HDL receptor that
mediates removal of HDL-cholesteryl esters (CE). However, its role in human lipoprotein …

High-density lipoproteins (HDLs) are athero-protective, primarily because of their ability to
promote cholesterol flux from peripheral tissues to the liver by reverse cholesterol transport …

The high-density lipoprotein (HDL) receptor scavenger receptor class B, type I (SR-BI), binds
HDL and mediates selective cholesteryl ester uptake. SR-BI's structure and mechanism are …

New findings underscore the importance of SR-BI-mediated SLU in hepatic SLU and RCT,
while indicating that further investigation is needed to define SLU pathways, including SR-BI …

The interaction of high-density lipoprotein (HDL) with its receptor, scavenger receptor BI (SR-
BI), is critical for lowering plasma cholesterol levels and reducing the risk for cardiovascular …