Protein assembly by design

J Zhu, N Avakyan, A Kakkis, AM Hoffnagle… - Chemical …, 2021 - ACS Publications
Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

Rationally programming nanomaterials with DNA for biomedical applications

L He, J Mu, O Gang, X Chen - Advanced Science, 2021 - Wiley Online Library
DNA is not only a carrier of genetic information, but also a versatile structural tool for the
engineering and self‐assembling of nanostructures. In this regard, the DNA template has …

Precise assembly of proteins and carbohydrates for next-generation biomaterials

L Li, G Chen - Journal of the American Chemical Society, 2022 - ACS Publications
The complexity and diversity of biomacromolecules make them a unique class of building
blocks for generating precise assemblies. They are particularly available to a new …

Controlling the DNA hybridization chain reaction

CA Figg, PH Winegar, OG Hayes… - Journal of the American …, 2020 - ACS Publications
A novel method for controlling the oligomerization of metastable DNA hairpins using the
hybridization chain reaction (HCR) is reported. Control was achieved through the …

Protein transfection via spherical nucleic acids

SB Ebrahimi, D Samanta, CD Kusmierz, CA Mirkin - Nature Protocols, 2022 - nature.com
The efficient transfection of functional proteins into cells can serve as a means for regulating
cellular processes toward solving fundamental challenges in biology and medicine …

Modular Protein–DNA Cocrystals as Precise, Programmable Assembly Scaffolds

AR Orun, ET Shields, S Dmytriw, A Vajapayajula… - ACS …, 2023 - ACS Publications
High-precision nanomaterials to entrap DNA-binding molecules are sought after for
applications such as controlled drug delivery and scaffold-assisted structural biology. Here …

Engineering of protein crystals for use as solid biomaterials

M Kojima, S Abe, T Ueno - Biomaterials Science, 2022 - pubs.rsc.org
Protein crystals have attracted a great deal of attention as solid biomaterials because they
have porous structures created by regular assemblies of proteins. The lattice structures of …

Protein assembly: Controllable design strategies and applications in biology

Y Li, R Tian, H Shi, J Xu, T Wang, J Liu - Aggregate, 2023 - Wiley Online Library
Protein assembly is the structural basis for the collaboration between proteins to accomplish
life activities due to its realization of the domain‐limited and precise spatial arrangement of …

Programmable cocrystallization of DNA origami shapes

M Ji, J Liu, L Dai, L Wang, Y Tian - Journal of the American …, 2020 - ACS Publications
Assembly of distinct types of species, particularly possessing anisotropic configurations, is
the premise to broaden structural diversity and explore materials' collective properties …

Dna-templated anchoring of proteins for programmable cell functionalization and immunological response

M Xiong, G Kong, Q Liu, L Liu, Y Yin, Y Liu, H Yuan… - Nano Letters, 2022 - ACS Publications
Membrane protein engineering exhibits great potential for cell functionalization. Although
genetic strategies are sophisticated for membrane protein engineering, there still exist some …