As a result of cross-species transmission in December 2019, the coronavirus disease 2019
(COVID-19) became a serious endangerment to human health and the causal agent of a …

Cell therapy is one of the new treatment methods in which mesenchymal stem/stromal cell
(MSCs) transplantation is one of the cells widely used in this field. The results of MSCs …

Rationale: Ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) that
is associated with high morbidity and mortality, and for which specific treatments are lacking …

Aims This study aims to verify the molecular mechanism that Tripartite motif containing 21
(TRIM21) promotes ubiquitination degradation of glutathione peroxidase 4 (GPX4) by …

Cell-based therapeutics are novel therapeutic strategies that can potentially treat many
presently incurable diseases through novel mechanisms of action. Cell therapies may …

The outbreak of COVID-19 in December 2019, has become an urgent and serious public
health emergency. At present, there is no effective treatment or vaccine for COVID-19 …

Mesenchymal stem cells (MSCs) are a type of versatile adult stem cells present in various
organs. These cells give rise to extracellular vesicles (EVs) containing a diverse array of …

Stem cell therapy has been used to treat several types of diseases, and it is expected that its
therapeutic uses shall increase as novel lines of evidence begin to appear. Furthermore …

Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …

Aim Increasing evidence demonstrated circular RNAs (circRNAs) are involved in the
development of various diseases, including sepsis-induced AKI. Although CIRC-Ttc3 has …