General anesthesia is characterized by loss of consciousness, amnesia, analgesia, and
immobility. Important molecular targets of general anesthetics have been identified, but the …

Sleep and wakefulness control in the mammalian brain requires the coordination of various
discrete interconnected neurons. According to the most conventional sleep model, wake …

Astrocytes are fundamental building blocks of the central nervous system. Their dysfunction
has been implicated in many psychiatric disorders, including alcohol use disorder, yet our …

Consumption of a high-fat diet (HFD) has been associated with reduced wakefulness and
various behavioral deficits, including anxiety, depression, and anhedonia. The …

For more than 60 years, dopamine (DA) has been known as a critical modulatory
neurotransmitter regulating locomotion, reward-based motivation, and endocrine functions …

Sleep is crucial for brain development. Sleep disturbances are prevalent in children with
autism spectrum disorder (ASD). Strikingly, these sleep problems are positively correlated …

Consciousness, defined as being aware of and responsive to one's surroundings, is
characteristic of normal waking life and typically is lost during sleep and general …

GABAergic neurons in the ventral tegmental area (VTA) have brain-wide projections and are
involved in multiple behavioral and physiological functions. Here, we revealed the …

Obesity is a costly, global epidemic that is perpetuated by an unhealthy diet. A significant
factor in the initial consumption and maintenance of an unhealthy diet is the abundance of …

Aim This preliminary investigation evaluated the link between alcohol craving and insomnia
in actively drinking patients with alcohol dependence (AD). Methods We conducted a …