Evidence for the benefits of melatonin in cardiovascular disease

M Tobeiha, A Jafari, S Fadaei, SMA Mirazimi… - Frontiers in …, 2022 - frontiersin.org
The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …

Endothelial dysfunction in experimental models of arterial hypertension: cause or consequence?

I Bernatova - BioMed research international, 2014 - Wiley Online Library
Hypertension is a risk factor for other cardiovascular diseases and endothelial dysfunction
was found in humans as well as in various commonly employed animal experimental …

Wine polyphenols improve cardiovascular remodeling and vascular function in NO-deficient hypertension

I Bernátová, O Pechánová, P Babál… - American Journal …, 2002 - journals.physiology.org
The effects of the red wine polyphenolic compounds (Provinol) on hypertension, left
ventricular hypertrophy, myocardial fibrosis, and vascular remodeling were investigated after …

Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB

JL Miguel-Carrasco, S Zambrano, AJ Blanca… - Journal of …, 2010 - Springer
Background Captopril is an angiotensin-converting enzyme (ACE) inhibitor widely used in
the treatment of arterial hypertension and cardiovascular diseases. Our objective was to …

[PDF][PDF] Participation of nitric oxide in different models of experimental hypertension.

J Török - Physiological research, 2008 - biomed.cas.cz
Participation of Nitric Oxide in Different Models of Experimental Hypertension Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2008 …

Red wine polyphenols prevent cardiovascular alterations in L-NAME-induced hypertension

O Pechánová, I Bernátová, P Babál… - Journal of …, 2004 - journals.lww.com
Objective Red wine polyphenols have been reported to possess beneficial properties for
preventing cardiovascular diseases but their effects on hemodynamic and functional …

Hesperidin prevents nitric oxide deficiency-induced cardiovascular remodeling in rats via suppressing TGF-β1 and MMPs protein expression

P Maneesai, S Bunbupha, P Potue, T Berkban… - Nutrients, 2018 - mdpi.com
Hesperidin is a major flavonoid isolated from citrus fruits that exhibits several biological
activities. This study aims to evaluate the effect of hesperidin on cardiovascular remodeling …

The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760

S Cacanyiova, M Cebova, F Simko, T Baka… - Biological Research, 2023 - Springer
Background Angiotensin converting enzyme 2 (ACE2) plays a crucial role in the infection
cycle of SARS-CoV-2 responsible for formation of COVID-19 pandemic. In the …

Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension

F Simko, T Baka, K Krajcirovicova, K Repova… - Molecules, 2018 - mdpi.com
The renin-angiotensin-aldosterone system (RAAS) is a dominant player in several
cardiovascular pathologies. This study investigated whether alterations induced by l …

Taxifolin reduces blood pressure via improvement of vascular function and mitigating the vascular inflammatory response in spontaneously hypertensive rats

S Liskova, S Cacanyiova, M Cebova… - International Journal of …, 2023 - mdpi.com
The effect of a 10-day-long treatment with taxifolin (TAX, 20 mg/kg/day po) was investigated
on spontaneously hypertensive rats (SHRs) with a focus on the vascular functions of isolated …