Genetics of human female infertility
SA Yatsenko, A Rajkovic - Biology of reproduction, 2019 - academic.oup.com
About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
Premature ovarian insufficiency: new perspectives on genetic cause and phenotypic spectrum
Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …
[HTML][HTML] Update on genetic predisposition to colorectal cancer and polyposis
The present article summarizes recent developments in the characterization of genetic
predisposition to colorectal cancer (CRC). The main themes covered include new hereditary …
predisposition to colorectal cancer (CRC). The main themes covered include new hereditary …
Genetics of primary ovarian insufficiency
Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the
age of 40 and account for one major cause of female infertility. POI relevance is continuously …
age of 40 and account for one major cause of female infertility. POI relevance is continuously …
Advances in the molecular pathophysiology, genetics, and treatment of primary ovarian insufficiency
I Huhtaniemi, O Hovatta, A La Marca, G Livera… - Trends in Endocrinology …, 2018 - cell.com
Primary ovarian insufficiency (POI) affects∼ 1% of women before 40 years of age. The
recent leap in genetic knowledge obtained by next generation sequencing (NGS) together …
recent leap in genetic knowledge obtained by next generation sequencing (NGS) together …
Meiosis interrupted: the genetics of female infertility via meiotic failure
Idiopathic or “unexplained” infertility represents as many as 30% of infertility cases
worldwide. Conception, implantation, and term delivery of developmentally healthy infants …
worldwide. Conception, implantation, and term delivery of developmentally healthy infants …
Premature ovarian insufficiency
SM McGlacken-Byrne, GS Conway - Best Practice & Research Clinical …, 2022 - Elsevier
The natural lifespan of the ovary is occasionally interrupted by pathological processes; some
are known, but many are unknown. Premature ovarian insufficiency (POI) can be a …
are known, but many are unknown. Premature ovarian insufficiency (POI) can be a …
MCM8 and MCM9 Nucleotide Variants in Women With Primary Ovarian Insufficiency
S Desai, M Wood-Trageser, J Matic… - The Journal of …, 2017 - academic.oup.com
Objective: To assess the frequency of variants, including biallelic pathogenic variants, in
minichromosome maintenance 8 (MCM8) and minichromosome maintenance 9 (MCM9) …
minichromosome maintenance 8 (MCM8) and minichromosome maintenance 9 (MCM9) …
[HTML][HTML] Recent discoveries in the genetics of familial colorectal cancer and polyposis
L Valle - Clinical Gastroenterology and Hepatology, 2017 - Elsevier
The development of genome-wide massively parallel sequencing, ie, whole-genome and
whole-exome sequencing, and copy number approaches has raised high expectations for …
whole-exome sequencing, and copy number approaches has raised high expectations for …
Whole-exome sequencing in patients with premature ovarian insufficiency: early detection and early intervention
H Liu, X Wei, Y Sha, W Liu, H Gao, J Lin, Y Li… - Journal of ovarian …, 2020 - Springer
Background The loss of ovarian function in women, referred to as premature ovarian
insufficiency (POI), is associated with a series of concomitant diseases. POI is genetically …
insufficiency (POI), is associated with a series of concomitant diseases. POI is genetically …