Recent advances in computer vision and machine learning underpin a collection of
algorithms with an impressive ability to decipher the content of images. These deep learning …

Bacterial physiology is a branch of biology that aims to understand overarching principles of
cellular reproduction. Many important issues in bacterial physiology are inherently …

Advances in microscopy hold great promise for allowing quantitative and precise
measurement of morphological and molecular phenomena at the single-cell level in …

The intestinal microbiota provides colonization resistance against pathogens, limiting
pathogen expansion and transmission. These microbiota-mediated mechanisms were …

The rise of antibiotic resistance and declining discovery of new antibiotics has created a
global health crisis. Of particular concern, no new antibiotic classes have been approved for …

The bacterial division apparatus catalyses the synthesis and remodelling of septal
peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles …

MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments
move around the rod circumference, helping to insert cell wall in the radial direction to …

During growth, cells must expand their cell volumes in coordination with biomass to control
the level of cytoplasmic macromolecular crowding. Dry-mass density, the average ratio of …

Cell shape matters across the kingdoms of life, and cells have the remarkable capacity to
define and maintain specific shapes and sizes. But how are the shapes of micron-sized cells …

Cell shape and cell-envelope integrity of bacteria are determined by the peptidoglycan cell
wall. In rod-shaped Escherichia coli, two conserved sets of machinery are essential for cell …