The mammalian cerebellum is located in the posterior cranial fossa and is critical for motor
coordination and non-motor functions including cognitive and emotional processes. The …

The ability to respond to genotoxic stress is a prerequisite for the successful development of
the nervous system. Mutations in various DNA repair factors can lead to human diseases …

We previously obtained evidence for reduced cell proliferation in the dentate gyrus (DG) of
fetuses with Down syndrome (DS), suggesting that the hippocampal hypoplasia seen in …

Although an association between air pollution and adverse systemic health effects has been
known for years, the effect of pollutants on neurodevelopment has been underappreciated …

BOLD fMRI (blood oxygenation level dependent functional magnetic resonance imaging) is
increasingly used to detect developmental changes of human brain function that are …

Mouse embryonic stem (ES) cells were used as an experimental model to study the effects
of electromagnetic fields (EMF). ES‐derived nestin‐positive neural progenitor cells were …

Down syndrome (DS) is characterized by brain hypotrophy and intellectual disability starting
from early life stages. Accumulating evidence shows that the phenotypic features of the DS …

The repair of DNA double-strand breaks (DSBs) occurs via nonhomologous end-joining
(NHEJ) or homologous recombination (HR). These mechanistically distinct pathways are …

During the third trimester, the human brain undergoes rapid cellular and molecular
processes that reshape the structural architecture of the cerebral cortex. Knowledge of …

Extremely low-gestational-age newborns have a prominently increased risk of brain
dysfunctions attributed to white-matter damage, which is thought to result from the …