Advances in molecular diagnosis of tuberculosis
Molecular tests for tuberculosis (TB) have the potential to help reach the three million people
with TB who are undiagnosed or not reported each year and to improve the quality of care …
with TB who are undiagnosed or not reported each year and to improve the quality of care …
[HTML][HTML] Silicosis, tuberculosis and silica exposure among artisanal and small-scale miners: a systematic review and modelling paper
An estimated 44 million artisanal and small-scale miners (ASM), largely based in developing
economies, face significant occupational risks for respiratory diseases which have not been …
economies, face significant occupational risks for respiratory diseases which have not been …
Xpert MTB/RIF ultra is highly sensitive for the diagnosis of tuberculosis lymphadenitis in a High-HIV setting
Tuberculosis lymphadenitis (TBL) is the most common extrapulmonary tuberculosis (EPTB)
manifestation. Xpert MTB/RIF Ultra (Ultra) is a World Health Organization-endorsed …
manifestation. Xpert MTB/RIF Ultra (Ultra) is a World Health Organization-endorsed …
[HTML][HTML] Evaluation of trace calls by Xpert MTB/RIF ultra for clinical management in low TB burden settings
A Amedeo, G Beci, M Giglia, G Lombardi, F Bisognin… - PLoS …, 2022 - journals.plos.org
Background Clinical interpretation of trace results by Xpert MTB/RIF Ultra assay (Ultra) used
as an initial diagnostic test for tuberculosis (TB) may be challenging. The aim of the study …
as an initial diagnostic test for tuberculosis (TB) may be challenging. The aim of the study …
[HTML][HTML] Tracing TB: are there predictors for active TB disease in patients with Xpert Ultra trace results?
WB Dowling, A Whitelaw, P Nel - International Journal of Infectious …, 2022 - Elsevier
Abstract Objectives The Xpert MTB/Rif Ultra (Xpert Ultra; Cepheid, USA) has increased
sensitivity compared with its predecessor (Gene Xpert), due to the addition of multicopy …
sensitivity compared with its predecessor (Gene Xpert), due to the addition of multicopy …
Comparison of Xpert MTB/RIF Ultra with Xpert MTB/RIF for the detection of Mycobacterium tuberculosis and rifampicin resistance in a primary-level clinic in rural China
M Li, Y Qiu, M Guo, R Qu, F Tian, G Wang, Y Wang… - Tuberculosis, 2023 - Elsevier
Abstract The Xpert MTB/RIF Ultra (Ultra) is not yet used for the diagnosis of tuberculosis (TB)
in China. We compared the performance of the Xpert and Ultra for detecting Mycobacterium …
in China. We compared the performance of the Xpert and Ultra for detecting Mycobacterium …
The practical value of Xpert MTB/RIF Ultra for diagnosis of pulmonary tuberculosis in a high tuberculosis burden setting: a prospective multicenter diagnostic accuracy …
G Wang, M Huang, H Jing, J Jia, L Dong… - Microbiology …, 2022 - Am Soc Microbiol
Due to the probability of decreased specificity, the practical value of performing the Xpert
MTB/RIF Ultra (Xpert Ultra) assay over the Xpert assay for diagnosing pulmonary …
MTB/RIF Ultra (Xpert Ultra) assay over the Xpert assay for diagnosing pulmonary …
Hepatocellular injury in children treated for rifampicin-resistant tuberculosis: incidence, etiology and outcome
J Duvenhage, HR Draper, AJ Garcia-Prats… - The Pediatric …, 2022 - journals.lww.com
Background: Hepatocellular injury has been reported commonly in adults on rifampicin-
resistant and multidrug-resistant tuberculosis (RR/MDR-TB) treatment. However, there are …
resistant and multidrug-resistant tuberculosis (RR/MDR-TB) treatment. However, there are …
Algorithms for Screening for Active Tuberculosis among Individuals with Latent Tuberculosis Infection in a Rural Community in China
H Xin, Y Du, X Cao, D Wang, B Zhang… - Microbiology …, 2022 - Am Soc Microbiol
Screening for active tuberculosis (TB) among individuals with latent tuberculosis infection
(LTBI) is important for the initiation and evaluation of TB preventive treatment. The …
(LTBI) is important for the initiation and evaluation of TB preventive treatment. The …
Progress toward developing sensitive non-sputum-based tuberculosis diagnostic tests: the promise of urine cell-free DNA
E MacLean, RR Nathavitharana - Journal of Clinical Microbiology, 2021 - Am Soc Microbiol
ABSTRACT A highly accurate, non-sputum-based test for tuberculosis (TB) detection is a
key priority for the field of TB diagnostics. A recent study in the Journal of Clinical …
key priority for the field of TB diagnostics. A recent study in the Journal of Clinical …