A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke

PD Lyden, MA Diniz, F Bosetti, J Lamb… - Science translational …, 2023 - science.org
Human diseases may be modeled in animals to allow preclinical assessment of putative
new clinical interventions. Recent, highly publicized failures of large clinical trials called into …

Prevention of postoperative cognitive dysfunction by minocycline in elderly patients after total knee arthroplasty: a randomized, double-blind, placebo-controlled …

T Takazawa, T Horiuchi, M Orihara, K Nagumo… - …, 2023 - pubs.asahq.org
Background There are no effective pharmacologic interventions for preventing postoperative
cognitive dysfunction in daily practice. Since the antibiotic minocycline is known to suppress …

Acute retinal necrosis: signs, treatment, complications and outcome

CS Mayer, K Blobner, J Storr, ID Baur, R Khoramnia - Diagnostics, 2022 - mdpi.com
Background: The Acute Retinal Necrosis (ARN) is an inflammatory, rapidly progressive
necrotizing retinitis and vasculitis, most frequently caused by Varicella-Zoster-Virus (VZV) …