Cystic fibrosis (CF), a monogenic disease caused by mutations in the CFTR gene on
chromosome 7, is complex and greatly variable in clinical expression. Airways, pancreas …

Cystic fibrosis (CF) is the most common autosomal-recessive cause of early mortality in
caucasians worldwide. 1 However, significant advances in therapies and outcomes for …

Polymorphonuclear neutrophils (PMNs) figure prominently in host defense against infection
and in noninfectious inflammation. Mobilized early in an inflammatory response, PMNs …

Cystic fibrosis (CF), is an autosomal recessive disease affecting different organs. The lung
disease, characterized by recurrent and chronic bacterial infection and inflammation since …

Cystic fibrosis-related diabetes (CFRD) is the most common comorbidity in patients with
cystic fibrosis (CF). Prevalence of CFRD increases with age and is greater with severe …

Treatment for cystic fibrosis (CF) has conventionally targeted downstream consequences of
the defect such as mucus plugging and infection. More recently, significant advances have …

Aspergillus fumigatus is the most frequent filamentous fungus isolated from respiratory
specimens from patients with cystic fibrosis (CF). Triazoles are the most widely used …

Pseudomonas aeruginosa (PA), a nonlactose fermenting gram-negative bacillus, is a
common cause of nosocomial infections in critically ill or debilitated patients, particularly …

Purpose We examined cystic fibrosis (CF) patients and compared their clinical status at the
time of primary versus double lung re-transplantation (re-DLTx) in order to better understand …

The increase in life expectancy of patients with cystic fibrosis has come with new
comorbidities, particularly diabetes. The gradual development of glucose tolerance …