New perspectives in diabetic neuropathy
Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …
New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism
Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …
Mesenchymal stromal cell-derived exosomes ameliorate peripheral neuropathy in a mouse model of diabetes
B Fan, C Li, A Szalad, L Wang, W Pan, R Zhang… - Diabetologia, 2020 - Springer
Aims/hypothesis Diabetic peripheral neuropathy (DPN) is one of the major complications of
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …
Diabetic neuropathy and neuropathic pain: a (con) fusion of pathogenic mechanisms?
NA Calcutt - Pain, 2020 - journals.lww.com
Neuropathy will afflict over half of the estimated 460 million people worldwide who have
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …
Functional and structural changes of the blood-nerve-barrier in diabetic neuropathy
The incidence of diabetes mellitus is approaching global epidemic proportions and should
be considered a major health-care problem of modern societies in the twenty-first century …
be considered a major health-care problem of modern societies in the twenty-first century …
Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified …
B Fan, M Chopp, ZG Zhang, XS Liu - Experimental neurology, 2021 - Elsevier
Diabetic peripheral neuropathy (DPN) is one of the most prevalent chronic complications of
diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal …
diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal …
The conundrum of diabetic neuropathies—past, present, and future
L Ang, K Mizokami-Stout, SA Eid, M Elafros… - Journal of Diabetes and …, 2022 - Elsevier
Diabetic neuropathy (DN) remains arguably the most prevalent chronic complication in
people with both type 1 and type 2 diabetes, including in youth, despite changes in the …
people with both type 1 and type 2 diabetes, including in youth, despite changes in the …
Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss
Pathological sensations caused by peripheral painful neuropathy occurring in Type 2
diabetes mellitus (T2DM) are often described as 'sharp'and 'burning'and are commonly …
diabetes mellitus (T2DM) are often described as 'sharp'and 'burning'and are commonly …
Evolving concepts on the role of dyslipidemia, bioenergetics, and inflammation in the pathogenesis and treatment of diabetic peripheral neuropathy
AM Stino, AE Rumora, B Kim… - Journal of the Peripheral …, 2020 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is one of the most widespread and disabling
neurological conditions, accounting for half of all neuropathy cases worldwide. Despite its …
neurological conditions, accounting for half of all neuropathy cases worldwide. Despite its …
Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics
Background Peripheral neuropathy (PN) is a common complication in obesity, prediabetes,
and type 2 diabetes, though its pathogenesis remains incompletely understood. In a murine …
and type 2 diabetes, though its pathogenesis remains incompletely understood. In a murine …