Naringenin, widely distributed in fruits and vegetables, is endowed with antiviral and other
health beneficial activities, such as immune-stimulating and anti-inflammatory actions that …

The emergence of the SARS-CoV-2 pandemic has prompted scientists to search for an
efficient antiviral medicine to overcome the rapid spread and the marked increase in the …

HIV/AIDS stands as a global burden, and vaginal microbicides constitute a promising
strategy for topical pre-exposure prophylaxis. Preceding the development of a microbicide …

Trypanosoma brucei N-myristoyltransferase (Tb NMT) is an attractive therapeutic target for
the treatment of human African trypanosomiasis (HAT). From previous studies, we identified …

Objective: Phytotherapy is growing importance with the emergence of deadly diseases.
Prostate cancer is one such disease which is the most prevalent cancer afflicting men …

In this study, the anticholinesterase effects of the extracts and isolated compounds from the
roots of endemic Prangos uechtritzii Boiss & Hausskn (Apiaceae) are reported. A novel …

The effect of bioisosteric replacement of carboxamide linking group with sulfonamide linking
group, on alkaline phosphatase (AP) and carbonic anhydrase (CA) inhibition activity of …

A comprehensive safety evaluation of chemicals should require toxicity assessment in both
the aquatic and terrestrial test species. Due to the application practices and nature of …

Human intestinal absorption (HIA) of the drugs administered through the oral route
constitutes an important criterion for the candidate molecules. The computational approach …

Three series of 4-hydroxy-N′-[benzylidene/1-phenylethylidene]-2-H/methyl/benzyl-1, 2-
benzothiazine-3-carbohydrazide 1, 1-dioxides (9–11) al were synthesized and unraveled to …