[HTML][HTML] Tight junctions and their regulation by non-coding RNAs

X Zhao, H Zeng, L Lei, X Tong, L Yang… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Tight junction (TJ) is a “zippering up” junction structure located at the uppermost portion of
adjacent epithelial/endothelial cells in organs and tissues. TJs maintain the relative stability …

Regeneration of the heart: from molecular mechanisms to clinical therapeutics

QY Guo, JQ Yang, XX Feng, YJ Zhou - Military Medical Research, 2023 - Springer
Heart injury such as myocardial infarction leads to cardiomyocyte loss, fibrotic tissue
deposition, and scar formation. These changes reduce cardiac contractility, resulting in heart …

Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery

AH Gheinani, M Vögeli, U Baumgartner, E Vassella… - Scientific reports, 2018 - nature.com
Circulating miRNAs are detected in extracellular space and body fluids such as urine.
Circulating RNAs can be packaged in secreted urinary extracellular vesicles (uEVs) and …

microRNA regulation of Wnt signaling pathways in development and disease

JL Song, P Nigam, SS Tektas, E Selva - Cellular signalling, 2015 - Elsevier
Wnt signaling pathways and microRNAs (miRNAs) are critical regulators of development.
Aberrant Wnt signaling pathways and miRNA levels lead to developmental defects and …

The role of vascular smooth muscle cells in the physiology and pathophysiology of blood vessels

L Bacakova, M Travnickova, E Filova… - Muscle Cell and …, 2018 - books.google.com
Vascular smooth muscle cells (VSMCs) play important roles not only in the physiological
functions of the blood vessels, such as vasoconstriction, vasodilatation and extracellular …

MicroRNA dysregulation in cutaneous squamous cell carcinoma

N García-Sancha, R Corchado-Cobos… - International journal of …, 2019 - mdpi.com
Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans
and it can be locally invasive and metastatic to distant sites. MicroRNAs (miRNAs or miRs) …

SNHG9/miR-199a-5p/Wnt2 axis regulates cell growth and aerobic glycolysis in glioblastoma

H Zhang, D Qin, Z Jiang, J Zhang - Journal of Neuropathology & …, 2019 - academic.oup.com
Aerobic glycolysis is a characteristic in cancers that is important for cancer cell proliferation.
Emerging evidence shows that long non-coding RNA (LncRNA) participates in glucose …

miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1

WT Wei, XX Nian, SY Wang, HL Jiao, YX Wang… - Cancer cell …, 2017 - Springer
Background miRNAs are regarded as molecular biomarkers and therapeutic targets for
colorectal cancer (CRC), a series of miRNAs have been proven to involve into CRC …

Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

M Li, N Zhang, W Zhang, W Hei, C Cai, Y Yang, C Lu… - BMC genomics, 2021 - Springer
Abstract Background Circular RNA (circRNA), a novel class of non-coding RNA, has a
closed-loop structure with important functions in skeletal muscle growth. The purpose of this …

Upregulation of miR-199a-5p protects spinal cord against ischemia/reperfusion-induced injury via downregulation of ECE1 in rat

N Bao, B Fang, H Lv, Y Jiang, F Chen, Z Wang… - Cellular and Molecular …, 2018 - Springer
Abstract Ischemia–reperfusion (I/R)-induced spinal cord injury can cause apoptotic damage
and subsequently act as a blood–spinal cord barrier damage. MicroRNAs (miRNAs) …