Chimeric galectin-3 and collagens: Biomarkers and potential therapeutic targets in fibroproliferative diseases

P Nangia-Makker, V Hogan, V Balan, A Raz - Journal of Biological …, 2022 - ASBMB
Fibrosis, stiffening and scarring of an organ/tissue due to genetic abnormalities,
environmental factors, infection, and/or injury, is responsible for> 40% of all deaths in the …

[HTML][HTML] Roles of biomarkers in myocardial fibrosis

Y Ding, Y Wang, W Zhang, Q Jia, X Wang, Y Li… - Aging and …, 2020 - ncbi.nlm.nih.gov
Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in
the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the …

Detection of myocardial fibrosis: where we stand

L Zhu, Y Wang, S Zhao, M Lu - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Myocardial fibrosis, resulting from the disturbance of extracellular matrix homeostasis in
response to different insults, is a common and important pathological remodeling process …

A Review on the Applications of Natural Biodegradable Nano Polymers in Cardiac Tissue Engineering

R Aziz, M Falanga, J Purenovic, S Mancini, P Lamberti… - Nanomaterials, 2023 - mdpi.com
As cardiac diseases, which mostly result in heart failure, are increasing rapidly worldwide,
heart transplantation seems the only solution for saving lives. However, this practice is not …

[PDF][PDF] Ghrelin ameliorated inflammation and oxidative stress in isoproterenol induced myocardial infarction through the endothelial nitric oxide synthase (eNOS) …

NO El-Shaer, WB El Gazzar, MM Allam… - Journal of Physiology & …, 2021 - jpp.krakow.pl
Although there is accumulating evidence which suggests that the administration of ghrelin
could be used to preserve cardiac function, delay the progression of heart failure post …

Effects of exercise training on behavior and brain function after high dose isoproterenol-induced cardiac damage

K Tóth, T Oroszi, EA van der Zee, C Nyakas… - Scientific Reports, 2021 - nature.com
Acute sympathetic stress can result in cardiac fibrosis, but may also lead to mental
dysfunction. Exercise training after isoproterenol (ISO)-induced acute sympathetic stress …

Ventromedial hypothalamus activation aggravates hypertension myocardial remodeling through the sympathetic nervous system

Y Zhou, Z Liu, Z Liu, H Zhou, X Xu, Z Li… - Frontiers in …, 2021 - frontiersin.org
Background: The ventromedial hypothalamus (VMH) is an important nuclei in responding to
emotional stress, and emotional stress is a risk factor for cardiovascular diseases. However …

N‐Acetylcysteine Slows Down Cardiac Pathological Remodeling by Inhibiting Cardiac Fibroblast Proliferation and Collagen Synthesis

J Zhou, J Xu, S Sun, M Guo, P Li, A Cheng - Disease Markers, 2021 - Wiley Online Library
Objective. By observing the effect of N‐acetylcysteine (NAC) on the proliferation and
collagen synthesis of rat cardiac fibroblasts (CFs) to explore the effect of NAC on cardiac …

[PDF][PDF] Iron chelation effects on lipid peroxidation, inflammation and ventricular performance in a rat model of isoproterenol induced acute myocardial stress.

M Lupu, DV TUDOR, VA TOMA, A Florea… - Journal of Physiology …, 2022 - researchgate.net
Acute cardiac pathologies represent one of the leading causes of death, while iron
metabolism is recognized to be implicated in reactive oxygen species production, lipid …

Sex dimorphism in isoproterenol-induced cardiac damage associated neuroinflammation and behavior in old rats

K Tóth, T Oroszi, EA van der Zee, C Nyakas… - Frontiers in Aging …, 2022 - frontiersin.org
Acute cardiac damage can be induced by isoproterenol injections in animals. The
associated inflammatory response could be reflected in the brain as neuroinflammation, with …