The evolutionarily conserved Forkhead box O (FOXO) family of transcription factors
regulates multiple transcriptional targets involved in various cellular processes, including …

It is estimated that in 2017 there were 451 million people with diabetes worldwide. These
figures are expected to increase to 693 million by 2045; thus, innovative preventative …

The development of acquired resistance to ErbB2 tyrosine kinase inhibitors limits the clinical
efficacy of this class of cancer therapeutics. Little is known about the mechanism (s) of …

Abstract The Forkhead box O (FoxO) family has recently been highlighted as an important
transcriptional regulator of crucial proteins associated with the many diverse functions of …

FOXO (forkhead box O) transcription factors are crucial regulators of cell fate. This function of
FOXO proteins relies on their ability to control diverse and at times, opposing cellular …

Diabetes refers to a group of metabolic diseases characterized by impaired insulin
signalling and high blood glucose. A growing body of epidemiological evidence links …

• Introduction• The caveolins• Caveolin‐1 in cell physiology‐Caveolin‐1 distribution‐
Caveolin‐1 and internalization‐Caveolin‐1 and cholesterol‐Regulation of caveolin‐1 …

Forkhead box O (FOXO) transcription factors are key players in diverse cellular processes
affecting tumorigenesis, stem cell maintenance and lifespan. To gain insight into the …

Caveolin-1 (cav-1), a 22-kDa transmembrane scaffolding protein, is the principal structural
component of caveolae. Cav-1 regulates critical cell functions including proliferation …

Caveolin-1, an essential scaffold protein of caveolae and cellular transport processes, lately
gained recognition as a stage-and tissue-specific tumor modulator in vivo. Patient studies …