The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …

The management of radioiodine refractory thyroid cancers (RAIR TC) is challenging for the
clinician. Tyrosine kinase inhibitors classically prescribed in this setting can fail due to …

The molecular mechanisms underlying the development of thyroid cancer (TC) have been
examined through extensive experiments. A large number of studies have shown that the …

Restoring sodium iodide symporter (NIS) expression and function remains a major
challenge for radioiodine therapy in anaplastic thyroid cancer (ATC). For more efficient …

Pancreatic ductal adenocarcinoma is one of the most aggressive solid tumours of the
pancreas, characterised by a five-year survival rate less than 8%. Recent reports that …

Anaplastic thyroid carcinoma (ATC), as one of the most aggressive human malignancies,
cannot be cured by 131iodine (131I) internal radiotherapy (RT) because the tumor cells …

Molecular imaging based personalized therapy has been a fascinating concept for
individualized therapeutic strategy, which is able to attain the highest efficacy and reduce …

Although most differentiated thyroid cancers show excellent prognosis, treating radioiodine
refractory differentiated thyroid cancer (RR-DTC) is challenging. Various therapies, including …

In the present study, we investigated whether bisphenol A (BPA) levels and excessive iodine
intake were associated with papillary thyroid carcinoma (PTC) and nodular goiter (NG). We …

Emerging evidence suggest that transcription factors play multiple roles in the development
of pancreatitis, a necroinflammatory condition lacking specific therapy. Estrogen-related …