Models of cardiac tissue electrophysiology are an important component of the Cardiac
Physiome Project, which is an international effort to build biophysically based multi-scale …

Mathematical modeling of cardiac electrophysiology is an insightful method to investigate
the underlying mechanisms responsible for arrhythmias such as atrial fibrillation (AF). In past …

Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …

Ongoing developments in cardiac modelling have resulted, in particular, in the development
of advanced and increasingly complex computational frameworks for simulating cardiac …

The most important ECG marker for the diagnosis of ischemia or infarction is a change in the
ST segment. Baseline wander is a typical artifact that corrupts the recorded ECG and can …

During the contraction of the ventricles, the ventricles interact with the atria as well as with
the pericardium and the surrounding tissue in which the heart is embedded. The atria are …

This paper examined the effects that different tissue conductivities had on forward-calculated
ECGs. To this end, we ranked the influence of tissues by performing repetitive forward …

Atrial myofiber orientation is complex and has multiple discrete layers and bundles. A novel
robust semi-automatic method to incorporate atrial anisotropy and heterogeneities into …

The loss of cardiac pump function accounts for a significant increase in both mortality and
morbidity in Western society, where there is currently a one in four lifetime risk, and costs …