Idiopathic pulmonary fibrosis

FJ Martinez, HR Collard, A Pardo, G Raghu… - Nature reviews Disease …, 2017 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by
progressive lung scarring and the histological picture of usual interstitial pneumonia (UIP). It …

Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat

TM Maher, ME Strek - Respiratory research, 2019 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a dismal prognosis. The
average life expectancy of untreated patients with IPF is only 3 to 4 years. Decline in forced …

Syndrome of combined pulmonary fibrosis and emphysema: an official ATS/ERS/JRS/ALAT research statement

V Cottin, M Selman, Y Inoue, AW Wong… - American journal of …, 2022 - atsjournals.org
Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …

Extracellular matrix in lung development, homeostasis and disease

Y Zhou, JC Horowitz, A Naba, N Ambalavanan… - Matrix Biology, 2018 - Elsevier
The lung's unique extracellular matrix (ECM), while providing structural support for cells, is
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …

Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis

KC Meyer - Expert review of respiratory medicine, 2017 - Taylor & Francis
Introduction: Many forms of interstitial lung disease (ILD) can progress to extensive fibrosis
and respiratory failure. Idiopathic pulmonary fibrosis (IPF), which generally has a poor …

Nintedanib in patients with idiopathic pulmonary fibrosis and preserved lung volume

M Kolb, L Richeldi, J Behr, TM Maher, W Tang… - Thorax, 2017 - thorax.bmj.com
Rationale There is no consensus as to when treatment for idiopathic pulmonary fibrosis (IPF)
should be initiated. Some physicians prefer not to treat patients with preserved lung volume …

Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema

M Chilosi, A Carloni, A Rossi, V Poletti - Translational Research, 2013 - Elsevier
Different anatomic and physiological changes occur in the lung of aging people that can
affect pulmonary functions, and different pulmonary diseases, including deadly diseases …

Interstitial lung disease

KM Antoniou, GA Margaritopoulos… - European …, 2014 - Eur Respiratory Soc
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …

Idiopathic pulmonary fibrosis: effects and optimal management of comorbidities

CS King, SD Nathan - The Lancet Respiratory Medicine, 2017 - thelancet.com
Despite the development of pharmacological therapies that are effective in slowing the
progression of idiopathic pulmonary fibrosis (IPF), it remains a debilitating and lethal …

[HTML][HTML] Natural history of idiopathic pulmonary fibrosis

HJ Kim, D Perlman, R Tomic - Respiratory medicine, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a parenchymal lung disease characterized by
progressive interstitial fibrosis. IPF has a poor prognosis, with a median survival time of 2–3 …