The regulatory role of microRNAs in breast cancer

HY Loh, BP Norman, KS Lai, NMANA Rahman… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNA molecules which function as critical post-
transcriptional gene regulators of various biological functions. Generally, miRNAs negatively …

Non-coding RNAs as regulators and markers for targeting of breast cancer and cancer stem cells

KS Prabhu, A Raza, T Karedath, SS Raza, H Fathima… - Cancers, 2020 - mdpi.com
Breast cancer is regarded as a heterogeneous and complicated disease that remains the
prime focus in the domain of public health concern. Next-generation sequencing …

[HTML][HTML] MiR-421 inhibits the malignant phenotype in glioma by directly targeting MEF2D

L Liu, S Cui, R Zhang, Y Shi, L Luo - American journal of cancer …, 2017 - ncbi.nlm.nih.gov
Abstract MicroRNA-421 (miRNA-421) dysregulation has been found in various human
tumors, however, the biological function and molecular mechanism of miR-421 in glioma …

microRNAs signature in relapse metastasis and de novo metastasis of breast cancer. A systematic review

C González-Martínez, C Garrido-Navas… - Critical reviews in …, 2023 - Elsevier
Abstract miRNAs have been widely identified as important players in cancer development
and progression. Metastasis in breast cancer can occur as relapse of a treated primary …

The role of micro RNAs in breast cancer metastasis: preclinical validation and potential therapeutic targets

UH Weidle, S Dickopf, C Hintermair… - Cancer Genomics & …, 2018 - cgp.iiarjournals.org
Despite the approval of several molecular therapies in the last years, breast cancer-
associated death ranks as the second highest in women. This is due to metastatic disease …

[HTML][HTML] LncRNA MEG3 inhibits self-renewal and invasion abilities of oral cancer stem cells by sponging miR-421

PY Chen, PL Hsieh, CY Peng, YW Liao, CH Yu… - Journal of the Formosan …, 2021 - Elsevier
Background/Purpose Oral cancer stem cells (CSCs) have been considered as the key cells
that are implicated in tumor recurrence and metastasis. In recent years, great attention has …

LncRNA AC093818. 1 accelerates gastric cancer metastasis by epigenetically promoting PDK1 expression

M Ba, Z Ba, H Long, S Cui, Y Gong, Z Yan, K Lin… - Cell Death & …, 2020 - nature.com
Gastric cancer (GC) is a highly prevalent type of metastatic tumor. The mechanisms
underlying GC metastasis are poorly understood. Some long noncoding RNAs (lncRNAs) …

Circulating microRNA Biomarker for Detecting Breast Cancer in High-Risk Benign Breast Tumors

VS Khadka, M Nasu, Y Deng, M Jijiwa - International Journal of Molecular …, 2023 - mdpi.com
High-risk benign breast tumors are known to develop breast cancer at high rates. However,
it is still controversial whether they should be removed during diagnosis or followed up until …

MRI-based breast cancer radiogenomics using RNA profiling: association with subtypes in a single-center prospective study

AY Park, MR Han, BK Seo, HY Ju, GS Son… - Breast Cancer …, 2023 - Springer
Background There are few prospective studies on the correlations between MRI features
and whole RNA-sequencing data in breast cancer according to molecular subtypes. The …

MicroRNA-421-targeted PDCD4 regulates breast cancer cell proliferation

Y Wang, Z Liu, J Shen - International Journal of …, 2019 - spandidos-publications.com
MicroRNAs (miRNAs) are expressed aberrantly in various types of cancer, and negatively
regulate the expression of target genes which may be useful in therapeutic strategies in …