The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association

C Iadecola, EE Smith, J Anrather, C Gu, A Mishra… - Stroke, 2023 - Am Heart Assoc
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

Impact of multiple pathologies on the threshold for clinically overt dementia

A Kapasi, C DeCarli, JA Schneider - Acta neuropathologica, 2017 - Springer
Longitudinal clinical–pathological studies have increasingly recognized the importance of
mixed pathologies (the coexistence of one or more neurodegenerative and cerebrovascular …

Detection, risk factors, and functional consequences of cerebral microinfarcts

SJ van Veluw, AY Shih, EE Smith, C Chen… - The Lancet …, 2017 - thelancet.com
Cerebral microinfarcts are small lesions that are presumed to be ischaemic. Despite the
small size of these lesions, affected individuals can have hundreds to thousands of cerebral …

The current role of MRI in differentiating multiple sclerosis from its imaging mimics

R Geraldes, O Ciccarelli, F Barkhof… - Nature Reviews …, 2018 - nature.com
MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS) …

Atrial Fibrillation and Cognitive Function: JACC Review Topic of the Week

HC Diener, RG Hart, PJ Koudstaal, DA Lane… - Journal of the American …, 2019 - jacc.org
Numerous vascular risk factors and vascular diseases contribute to cognitive impairment
and dementia. Many studies and registries show an association of atrial fibrillation (AF) with …

Predictive role of atrial fibrillation in cognitive decline: a systematic review and meta-analysis of 2.8 million individuals

YH Koh, LZW Lew, KB Franke, AD Elliott, DH Lau… - EP …, 2022 - academic.oup.com
Aims To systematic review and meta-analyse the association and mechanistic links between
atrial fibrillation (AF) and cognitive impairment. Methods and results PubMed, EMBASE, and …

Early-onset and delayed-onset poststroke dementia—revisiting the mechanisms

VCT Mok, BYK Lam, A Wong, H Ko… - Nature Reviews …, 2017 - nature.com
Incident stroke has long been recognized to cause dementia shortly after the event. Patients
who survive stroke without early-onset poststroke dementia (PSD) are at a high risk of …

Psychological aspects of atrial fibrillation: a systematic narrative review: impact on incidence, cognition, prognosis, and symptom perception

KH Ladwig, A Goette, S Atasoy, H Johar - Current cardiology reports, 2020 - Springer
Purpose of the review Atrial fibrillation (AF) is the most frequent arrhythmia in the general
population. This review aims to provide a comprehensive overview of the psychological …

High burden of cerebral white matter lesion in 9 Asian cities

BYK Lam, B Yiu, E Ampil, CLH Chen, Y Dikot… - Scientific Reports, 2021 - nature.com
Age-related white matter lesion (WML) is considered a manifestation of sporadic cerebral
small vessel disease and an important pathological substrate for dementia. Asia is notable …

[HTML][HTML] Direct oral anticoagulants are associated with lower risk of dementia in patients with atrial fibrillation

D Sagris, G Ntaios, BJR Buckley, SL Harrison… - European journal of …, 2024 - Elsevier
Background and aim Atrial fibrillation (AF) is associated with increased risk of dementia.
Whether direct oral anticoagulation (DOAC) reduce this risk compared to vitamin-K …