Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design
As the SARS-CoV-2 pandemic is rapidly progressing, the need for the development of an
effective vaccine is critical. A promising approach for vaccine development is to generate …
effective vaccine is critical. A promising approach for vaccine development is to generate …
Genome-wide analysis of codon usage patterns of SARS-CoV-2 virus reveals global heterogeneity of COVID-19
The ongoing outbreak of coronavirus disease COVID-19 is significantly implicated by global
heterogeneity in the genome organization of severe acute respiratory syndrome coronavirus …
heterogeneity in the genome organization of severe acute respiratory syndrome coronavirus …
Codon usage provides insights into the adaptive evolution of mycoviruses in their associated fungi host
Q Wang, X Lyu, J Cheng, Y Fu, Y Lin… - International Journal of …, 2022 - mdpi.com
Codon usage bias (CUB) could reflect co-evolutionary changes between viruses and hosts
in contrast to plant and animal viruses, and the systematic analysis of codon usage among …
in contrast to plant and animal viruses, and the systematic analysis of codon usage among …
Deep decoding of codon usage strategies and host adaption preferences of soybean mosaic virus
L Jiang, Q Zhang, S Xiao, F Si - International Journal of Biological …, 2022 - Elsevier
Soybean mosaic virus (SMV) has threatened the global yield of Leguminosae crops, but the
mechanism of its infection, spread, and evolution remains unknown. A systemic analysis of …
mechanism of its infection, spread, and evolution remains unknown. A systemic analysis of …
Codon-optimization in gene therapy: promises, prospects and challenges
AI Paremskaia, AA Kogan, A Murashkina… - … in Bioengineering and …, 2024 - frontiersin.org
Codon optimization has evolved to enhance protein expression efficiency by exploiting the
genetic code's redundancy, allowing for multiple codon options for a single amino acid …
genetic code's redundancy, allowing for multiple codon options for a single amino acid …
Molecular features similarities between SARS-CoV-2, SARS, MERS and key human genes could favour the viral infections and trigger collateral effects
LL Maldonado, AM Bertelli, L Kamenetzky - Scientific Reports, 2021 - nature.com
In December 2019, rising pneumonia cases caused by a novel β-coronavirus (SARS-CoV-2)
occurred in Wuhan, China, which has rapidly spread worldwide, causing thousands of …
occurred in Wuhan, China, which has rapidly spread worldwide, causing thousands of …
The adaptation of codon usage of+ ssRNA viruses to their hosts
L Tian, X Shen, RW Murphy, Y Shen - Infection, Genetics and Evolution, 2018 - Elsevier
Viruses depend on their host's cellular structure to survive. Most of them do not have tRNAs,
their translation relies on hosts' tRNA pools. Over the course of evolution, viruses needed to …
their translation relies on hosts' tRNA pools. Over the course of evolution, viruses needed to …
[HTML][HTML] Edging on mutational bias, induced natural selection from host and natural reservoirs predominates codon usage evolution in hantaan virus
G Ata, H Wang, H Bai, X Yao, S Tao - Frontiers in Microbiology, 2021 - frontiersin.org
The molecular evolutionary dynamics that shape hantaviruses' evolution are poorly
understood even now, besides the contribution of virus-host interaction to their evolution …
understood even now, besides the contribution of virus-host interaction to their evolution …
[HTML][HTML] Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonosis carried and
transmitted by infected rodents through urine, droppings, or saliva. The etiology of HFRS is …
transmitted by infected rodents through urine, droppings, or saliva. The etiology of HFRS is …
A detailed comparative analysis of codon usage bias in Alongshan virus
Alongshan virus (ALSV) is an emerging tick-borne pathogen that infects humans, causing
febrile disease. ALSV uses Ixodes Persulcatus ticks to infect humans with a wide range of …
febrile disease. ALSV uses Ixodes Persulcatus ticks to infect humans with a wide range of …