Chronic pain is highly prevalent among older adults where it is associated with significant
suffering, disability, social isolation, and greater costs and burden to health care systems …

Dementia is a progressive disease associated with irreversible impairment and loss of
cognitive abilities. About half of older people with dementia experience pain. In this paper …

Aging affects pain experience and brain functioning. However, how aging leads to changes
in pain perception and brain functional connectivity has not yet been completely understood …

Aging is associated with an increased risk of developing pain, especially in the presence of
concurrent chronic clinical conditions. Similarly, multimorbidity can affect the perception and …

Chronic pain, one of the most common reasons adults seek medical care, has been linked to
restrictions in mobility and daily activities, dependence on opioids, anxiety, depression …

The effects of neurodegeneration on the experience of pain remain poorly understood,
despite the risk of suffering from both pain and neurodegenerative diseases rising …

Spiking neural networks (SNNs) are artificial neural network models that more closely mimic
biological neural networks. In addition to neuronal and synaptic state, SNNs incorporate the …

Experimental pain research has shown that pain processing seems to be heightened in
dementia. It is unclear which neuropathological changes underlie these alterations. This …

Untreated pain in people with Alzheimer's disease continues to be a serious public health
problem. Pain is a subjective and complex experience that becomes increasingly …

Background: Sex differences in pain have been shown to exist in older adults with normal
cognition and people with Alzheimer's disease. It is unknown if sex differences in pain in …