In response to precision medicine: Current subcellular targeting strategies for cancer therapy
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
Molecular imaging: design mechanism and bioapplications
Molecular imaging is a non-invasive method to image and analyze the concentration and
activity of functional biomolecules in cells or in vivo at molecular level, and plays an …
activity of functional biomolecules in cells or in vivo at molecular level, and plays an …
Digital twin-driven architecture for AIoT-based energy service provision and optimal energy trading between smart nanogrids
This article explores integrating digital twin technology and blockchain within smart grids to
optimize energy trading among prosumers and consumers in smart nanogrids. Our platform …
optimize energy trading among prosumers and consumers in smart nanogrids. Our platform …
[HTML][HTML] Advances of aptamers screened by Cell-SELEX in selection procedure, cancer diagnostics and therapeutics
Y Zhong, J Zhao, J Li, X Liao, F Chen - Analytical biochemistry, 2020 - Elsevier
Aptamers are a class of short artificial single-stranded oligo (deoxy) nucleotides that can
bind to different targets, which generated by Systematic Evolution of Ligands by Exponential …
bind to different targets, which generated by Systematic Evolution of Ligands by Exponential …
Recent advances in aptamer applications for analytical biochemistry
G Zon - Analytical biochemistry, 2022 - Elsevier
Aptamers are typically defined as relatively short (20–60 nucleotides) single-stranded DNA
or RNA molecules that bind with high affinity and specificity to various types of targets …
or RNA molecules that bind with high affinity and specificity to various types of targets …
Cell‐SELEX, an effective way to the discovery of biomarkers and unexpected molecular events
T Bing, N Zhang, D Shangguan - Advanced biosystems, 2019 - Wiley Online Library
Cell‐SELEX can not only generate aptamers for specific cell isolation/detection, diagnosis,
and therapy, but also lead to the discovery of biomarkers and unexpected molecular events …
and therapy, but also lead to the discovery of biomarkers and unexpected molecular events …
Monodispersed and Monofunctionalized DNA‐Caged Au Nano‐Clusters with Enhanced Optical Properties for STED Imaging
L Qi, Y Xiao, X Fu, H Yang, L Fang, R Xu, J Ping, D Han… - Small, 2024 - Wiley Online Library
Abstract The performance of Stimulated Emission Depletion (STED) microscopy depends
critically on the fluorescent probe. Ultrasmall Au nanoclusters (Au NCs) exhibit large Stokes …
critically on the fluorescent probe. Ultrasmall Au nanoclusters (Au NCs) exhibit large Stokes …
Engineered aptamer for the analysis of cells
X Tang, C Feng, Q Pan, F Sun, X Zhu - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Since aptamers were discovered for about 30 years, they have already great capacity for
potential applications, like biosensor construction and bioanalysis. However, for more …
potential applications, like biosensor construction and bioanalysis. However, for more …
Electrochemiluminescence biosensor for nucleolin imaging in a single tumor cell combined with synergetic therapy of tumor
W Gao, Y Liu, H Zhang, Z Wang - ACS sensors, 2020 - ACS Publications
Nucleolin, a nuclear biological multifunctional protein, plays significant roles in modulating
the proliferation, survival, and apoptosis of tumor cells. Different from the traditional …
the proliferation, survival, and apoptosis of tumor cells. Different from the traditional …
A fluorescent probe targeting mitochondria and lipid droplets for visualization of cell death
L Zhu, L Huang, W Su, X Liang… - Chemistry–An Asian …, 2022 - Wiley Online Library
Subcellular organelles play an indispensable role in various biological process. Therefore, it
is very important to develop fluorescent probe to identify different organelles and their …
is very important to develop fluorescent probe to identify different organelles and their …