In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Molecular imaging: design mechanism and bioapplications

L Chen, Y Lyu, X Zhang, L Zheng, Q Li, D Ding… - Science China …, 2023 - Springer
Molecular imaging is a non-invasive method to image and analyze the concentration and
activity of functional biomolecules in cells or in vivo at molecular level, and plays an …

Digital twin-driven architecture for AIoT-based energy service provision and optimal energy trading between smart nanogrids

H Jamil, Y Jian, F Jamil, M Hijjawi, A Muthanna - Energy and Buildings, 2024 - Elsevier
This article explores integrating digital twin technology and blockchain within smart grids to
optimize energy trading among prosumers and consumers in smart nanogrids. Our platform …

[HTML][HTML] Advances of aptamers screened by Cell-SELEX in selection procedure, cancer diagnostics and therapeutics

Y Zhong, J Zhao, J Li, X Liao, F Chen - Analytical biochemistry, 2020 - Elsevier
Aptamers are a class of short artificial single-stranded oligo (deoxy) nucleotides that can
bind to different targets, which generated by Systematic Evolution of Ligands by Exponential …

Recent advances in aptamer applications for analytical biochemistry

G Zon - Analytical biochemistry, 2022 - Elsevier
Aptamers are typically defined as relatively short (20–60 nucleotides) single-stranded DNA
or RNA molecules that bind with high affinity and specificity to various types of targets …

Cell‐SELEX, an effective way to the discovery of biomarkers and unexpected molecular events

T Bing, N Zhang, D Shangguan - Advanced biosystems, 2019 - Wiley Online Library
Cell‐SELEX can not only generate aptamers for specific cell isolation/detection, diagnosis,
and therapy, but also lead to the discovery of biomarkers and unexpected molecular events …

Monodispersed and Monofunctionalized DNA‐Caged Au Nano‐Clusters with Enhanced Optical Properties for STED Imaging

L Qi, Y Xiao, X Fu, H Yang, L Fang, R Xu, J Ping, D Han… - Small, 2024 - Wiley Online Library
Abstract The performance of Stimulated Emission Depletion (STED) microscopy depends
critically on the fluorescent probe. Ultrasmall Au nanoclusters (Au NCs) exhibit large Stokes …

Engineered aptamer for the analysis of cells

X Tang, C Feng, Q Pan, F Sun, X Zhu - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Since aptamers were discovered for about 30 years, they have already great capacity for
potential applications, like biosensor construction and bioanalysis. However, for more …

Electrochemiluminescence biosensor for nucleolin imaging in a single tumor cell combined with synergetic therapy of tumor

W Gao, Y Liu, H Zhang, Z Wang - ACS sensors, 2020 - ACS Publications
Nucleolin, a nuclear biological multifunctional protein, plays significant roles in modulating
the proliferation, survival, and apoptosis of tumor cells. Different from the traditional …

A fluorescent probe targeting mitochondria and lipid droplets for visualization of cell death

L Zhu, L Huang, W Su, X Liang… - Chemistry–An Asian …, 2022 - Wiley Online Library
Subcellular organelles play an indispensable role in various biological process. Therefore, it
is very important to develop fluorescent probe to identify different organelles and their …