African swine fever virus interaction with host innate immune factors

AE Afe, ZJ Shen, X Guo, R Zhou, K Li - Viruses, 2023 - mdpi.com
African swine fever virus (ASFV) adversely affects pig farming owing to its 100% mortality
rate. The condition is marked by elevated body temperature, bleeding, and ataxia in …

Review of the pig-adapted African swine fever viruses in and outside Africa

ML Penrith, J Van Heerden, L Heath, EO Abworo… - Pathogens, 2022 - mdpi.com
The region in eastern, central and southern Africa (ECSA) where African swine fever (ASF)
originated in a sylvatic cycle is home to all the p72 genotypes of ASF virus identified so far …

Development of a new effective African swine fever virus vaccine candidate by deletion of the H240R and MGF505-7R genes results in protective immunity against the …

J Li, J Song, S Zhou, S Li, J Liu, T Li, Z Zhang… - Journal of …, 2023 - Am Soc Microbiol
African swine fever is a contagious and lethal disease of domestic pigs and wild boars,
which has caused significant economic loss for the swine industry. African swine fever virus …

Recombinant African swine fever virus Arm/07/CBM/c2 lacking CD2v and A238L is attenuated and protects pigs against virulent Korean Paju strain

D Pérez-Núñez, SY Sunwoo, R García-Belmonte… - Vaccines, 2022 - mdpi.com
African swine fever (ASF) is an obligated declaration swine disease, provoking farm
isolation measures and the closing of affected country boarders. ASF virus (ASFV) is …

Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review

J Fan, H Yu, F Miao, J Ke, R Hu - Microbiology Spectrum, 2024 - journals.asm.org
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic
losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains …

Making genome editing a success story in Africa

HM Abkallo, P Arbuthnot, TO Auer, DK Berger… - Nature …, 2024 - nature.com
Since the development of CRISPR–Cas as a tool for targeted genome manipulation in 2012,
genome editing has revolutionized basic and translational research around the globe 1. The …

Advances in CRISPR/Cas‐Based Strategies on Zoonosis

Y Zhang, Q Peng, R Zhang, C Li, Q Xu… - Transboundary and …, 2023 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated
(Cas) has emerged as the predominant technique for gene editing technique due to its high …

The potential of Chlorella spp. as antiviral source against African swine fever virus through a virtual screening pipeline

ANG Dulay, JCC de Guzman, ZYD Marquez… - Journal of Molecular …, 2024 - Elsevier
African swine fever (ASF) causes high mortality in pigs and threatens global swine
production. There is still a lack of therapeutics available, with two vaccines under scrutiny …

ASFV proteins presented at the surface of T7 phages induce strong antibody responses in mice

Y Li, R Sun, S Li, Z Tan, Z Li, Y Liu, Y Guo… - Journal of Virological …, 2023 - Elsevier
African swine fever virus (ASFV) infection causes substantial economic losses to the swine
industry worldwide, and there are still no safe and effective vaccines or therapeutics …

[HTML][HTML] African swine fever virus pB475L evades host antiviral innate immunity via targeting STAT2 to inhibit IFN-I signaling

Z Huang, Z Mai, C Kong, J You, S Lin, C Gao… - Journal of Biological …, 2024 - Elsevier
African swine fever virus (ASFV) causes severe disease in domestic pigs and wild boars,
seriously threatening the development of the global pig industry. Type I interferon (IFN-I) is …