Phytochemical composition of Clinacanthus nutans based on factors of environment, genetics and postharvest processes: A review

NH Sabindo, RM Yatim, PK Thirumulu - BioMedicine, 2024 - pmc.ncbi.nlm.nih.gov
Herpes simplex, varicella-zoster lesions, skin rashes, diabetes, snake bites and insect bites
have all been treated by using Clinacanthus nutans (C. nutans). The pharmacological …

Dichloromethane fraction of Moringa oleifera leaf methanolic extract selectively inhibits breast cancer cells (MCF7) by induction of apoptosis via upregulation of Bax …

UF Mohd Fisall, NZ Ismail, IA Adebayo… - Molecular biology reports, 2021 - Springer
Moringa oleifera is a well-known medicinal plant which has anti-cancer and other biological
activities. This research aims to determine the cytotoxic and apoptotic effect of M. oleifera …

GC‐MS Evaluation, Antioxidant Content, and Cytotoxic Activity of Propolis Extract from Peninsular Malaysian Stingless Bees, Tetrigona Apicalis

WAS Mohamed, NZ Ismail, EA Omar… - Evidence‐Based …, 2020 - Wiley Online Library
Introduction. Propolis has been used traditionally in several countries for treating various
diseases as it possessed healing properties including antioxidant and anticancer qualities …

Network pharmacology, molecular docking and molecular dynamics simulation of chalcone scaffold-based compounds targeting breast cancer receptors

NZ Ismail, M Khairuddean, S Abubakar… - Journal of Biomolecular …, 2023 - Taylor & Francis
Compounds with a chalcone scaffold-based structure have demonstrated promising
anticancer biological activity. However, the molecular interactions between chalcone …

The development of callus and cell suspension cultures of Sabah Snake Grass (Clinacanthus nutans) for the production of flavonoids and phenolics

FJ Bong, NJY Chear, S Ramanathan… - Biocatalysis and …, 2021 - Elsevier
Abstract Clinacanthus nutans (Burm. f.) Lindau is a valuable medicinal plant that has gained
interest as a side treatment for cancer in Southeast Asia. Phenolic and flavonoid compounds …

Antioxidant Effects, Antiproliferative Effects, and Molecular Docking of Clinacanthus nutans Leaf Extracts

NZ Ismail, Z Md Toha, M Muhamad… - Molecules, 2020 - mdpi.com
Clinacanthus nutans is a well-known herb that has been used as an alternative and
therapeutic medicine, however more selective C. nutans extracts are needed. In this study …

Christia vespertilionis extract induced antiproliferation and apoptosis in breast cancer (MCF7) cells

NZ Ismail, IA Adebayo, WAS Mohamed… - Molecular Biology …, 2021 - Springer
Background C. vespertiliomis extracts were evaluated for antiproliferative and apoptosis
effect on breast cancer (MCF7) cells. Methods and results The leaves extracts were …

Molecular docking and molecular dynamic simulations of apoptosis proteins with potential anticancer compounds present in Clinacanthus nutans extract using gas …

NZ Ismail, WAS Mohamed, N Ab. Rahim… - Journal of …, 2023 - Taylor & Francis
Clinacanthus nutans is a medicinal plant recognised for its anticancer properties. We
previously discovered that the C. nutans extract had the most potent inhibitory effect on …

The antiproliferative and apoptotic potential of Clinacanthus nutans against human breast cancer cells through targeted apoptosis pathway

NZ Ismail, S Md Saad, IA Adebayo, Z Md Toha… - … Science and Pollution …, 2022 - Springer
Clinacanthus nutans dichloromethane fraction (CN-Dcm) extract has previously been
proven to suppress breast cancer (MCF7) cell proliferation. Despite this, the extrinsic and …

Molecular docking of compounds from Clinacanthus nutans extract detected by GC-MS analysis with the SARS-CoV-2 main protease and ACE2 protein

NZ Ismail, IA Adebayo, NN Mohamad Zain… - Natural Product …, 2022 - Taylor & Francis
Clinacanthus nutans has been reported to have many medicinal properties and it is
traditionally used in treating viral lesions. This study aims to determine the molecular …