Metabolic diseases, such as obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D),
are now a widespread pandemic in the developed world. These pathologies show sex …

Bile acids are commonly known as digestive agents for lipids. The mechanisms of bile acids
in the gastrointestinal track during normal physiological conditions as well as hepatic and …

Background Epidemiological studies have shown Per-and polyfluoroalkyl substances
(PFAS) to be associated with diseases of dysregulated lipid and sterol homeostasis such as …

In brief Sex differences in the gut microbiome may impact multiple aspects of human health
and disease. In this study, we review the evidence for microbial sex differences in puberty …

The human gut microbiome has been linked to numerous digestive disorders, but its
metabolic products have been much less well characterized, in part due to the expense of …

Obesity and elevated serum lipids are associated with a threefold increase in the risk of
developing atherosclerosis, a condition that underlies stroke, myocardial infarction, and …

Recently, the concept of the brain-gut-microbiota (BGM) axis disturbances in the
pathogenesis of Alzheimer's disease (AD) has been receiving growing attention. At the …

Bile acids (BAs) are a group of important physiological agents for cholesterol metabolism,
intestinal nutrient absorption, and biliary secretion of lipids, toxic metabolites, and …

Bile acids (BA) play an important role in lipid metabolism. They facilitate intestinal lipid
absorption, and BA synthesis is the main catabolic pathway for cholesterol. The objective of …

Background Dysregulated bile acid (BA) metabolism has been linked to steatosis,
inflammation, and fibrosis in nonalcoholic fatty liver disease (NAFLD). Aim To determine …