Major advances have occurred in recent years in our understanding of HIV-1 assembly,
release and maturation, as work in this field has been propelled forwards by developments …

A defining property of retroviruses is their ability to assemble into particles that can leave
producer cells and spread infection to susceptible cells and hosts. Virion morphogenesis …

The HIV-1 Gag protein orchestrates all steps of virion genesis, including membrane
targeting and RNA recruitment into virions. Using crosslinking-immunoprecipitation (CLIP) …

Like all retroviruses, the human immunodeficiency virus selectively packages two copies of
its unspliced RNA genome, both of which are utilized for strand-transfer-mediated …

Gag, the primary structural protein of HIV-1, is recruited to the plasma membrane for virus
assembly by its matrix (MA) domain. Gag is subsequently cleaved into its component …

The plasma membrane is the final barrier that enveloped viruses must cross during their
egress from the infected cell. Here, we review recent insights into the cell biology of retroviral …

The HIV genome encodes a small number of viral proteins (ie, 16), invariably establishing
cooperative associations among HIV proteins and between HIV and host proteins, to invade …

As a member of the retrovirus family, HIV-1 packages its RNA genome into particles and
replicates through a DNA intermediate that integrates into the host cellular genome. The …

Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process
requiring the recruitment of viral and cellular components to the plasma membrane for …

During the late stage of the viral life cycle, HIV-1 Gag assembles into a spherical immature
capsid, and undergoes budding, release, and maturation. Here we review events involved in …