Emerging arrhythmic risk of autoimmune and inflammatory cardiac channelopathies

PE Lazzerini, PL Capecchi, N El‐Sherif… - Journal of the …, 2018 - Am Heart Assoc
Cardiac arrhythmias are associated with high morbidity and mortality. 1 Specifically,
malignant arrhythmias are a recognized leading cause of sudden cardiac death (SCD) in the …

[HTML][HTML] DICTrank: The largest reference list of 1318 human drugs ranked by risk of drug-induced cardiotoxicity using FDA labeling

Y Qu, T Li, Z Liu, D Li, W Tong - Drug Discovery Today, 2023 - Elsevier
Drug-induced cardiotoxicity (DICT) is a leading cause of drug trial failure and
discontinuation. Current drug annotations for cardiotoxicity largely focus on individual …

[图书][B] Simpson's forensic medicine

J Payne-James, RM Jones - 2019 - taylorfrancis.com
Prestigious and authoritative, this fully updated fourteenth edition of Simpson's Forensic
Medicine remains a classic; one of the world's leading introductory texts in the field of …

Role of pharmacogenetics in adverse drug reactions: an update towards personalized medicine

E Micaglio, ET Locati, MM Monasky… - Frontiers in …, 2021 - frontiersin.org
Adverse drug reactions (ADRs) are an important and frequent cause of morbidity and
mortality. ADR can be related to a variety of drugs, including anticonvulsants, anaesthetics …

Genetic and molecular aspects of drug-induced QT interval prolongation

D Baracaldo-Santamaría, K Llinás-Caballero… - International Journal of …, 2021 - mdpi.com
Long QT syndromes can be either acquired or congenital. Drugs are one of the many
etiologies that may induce acquired long QT syndrome. In fact, many drugs frequently used …

Acute exposure to low-dose bisphenol A delays cardiac repolarization in female canine heart–Implication for proarrhythmic toxicity in large animals

J Ma, PJ Niklewski, HS Wang - Food and Chemical Toxicology, 2023 - Elsevier
Bisphenol A (BPA) is a common environmental chemical with a range of potential adverse
health effects. The impact of environmentally-relevant low dose of BPA on the electrical …

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management

D Thomas, T Christ, L Fabritz, A Goette… - Clinical Research in …, 2019 - Springer
Cardiac arrhythmias remain a common challenge and are associated with significant
morbidity and mortality. Effective and safe rhythm control strategies are a primary, yet unmet …

Effect of maternal antidepressant use during the pre-pregnancy/early pregnancy period on congenital heart disease: A prospective cohort study in central China

M Sun, S Zhang, Y Li, L Chen, J Diao, J Li… - Frontiers in …, 2022 - frontiersin.org
Background With the increase in maternal antidepressant prescribing before/during
pregnancy, concerns about the safety of antidepressants have come into focus. The purpose …

Sarcoplasmic reticulum Ca2+ dysregulation in the pathophysiology of inherited arrhythmia: an update

Y Du, LJ Demillard, J Ren - Biochemical Pharmacology, 2022 - Elsevier
Inherited arrhythmias are the leading causes for cardiac arrest and sudden cardiac death
(SCD). Other than ion channel mutations, inherited arrhythmias including catecholaminergic …

Long QT syndrome and perioperative torsades de pointes: what the anesthesiologist should know

N Niimi, K Yuki, K Zaleski - Journal of Cardiothoracic and Vascular …, 2022 - jcvaonline.com
TORSADES DE pointes (TdP or “twisting of the points”) is a rare but potentially fatal
polymorphic ventricular tachycardia characterized by rapid, wide QRS complexes of …