Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Interest in the communication between the gastrointestinal tract and central nervous system,
known as the gut–brain axis, has prompted the development of quantitative analytical …

The human gut microbiome has emerged as a key player in the bidirectional communication
of the gut–brain axis, affecting various aspects of homeostasis and pathophysiology. Until …

Alterations in intestinal structure, mechanics and physiology underlie acute and chronic
intestinal conditions, many of which are influenced by dysregulation of microbiome …

The human gut microbiome is crucial to hosting physiology and health. Therefore, stable in
vitro coculture of primary human intestinal cells with a microbiome community is essential for …

Background: The central nervous system (CNS) known to regulate the physiological
conditions of human body, also itself gets dynamically regulated by both the physiological as …

Crypt-villus architecture in the small intestine is crucial for the structural integrity of the
intestinal epithelium and maintenance of gut homeostasis. We utilized three-dimensional …

We establish an in vitro perfusion intestinal tissue bioreactor system tailored to study drug
responses related to inflammatory bowel disease (IBD). The system includes key …

The gut microbiome (GM), the gut barrier, and the blood-brain barrier (BBB) are key
elements of the gut-brain axis (GBA). The advances in organ-on-a-chip and induced …

Designing biomimetic scaffolds with in vivo–like microenvironments using biomaterials is an
essential component of successful tissue engineering approaches. The intestinal smooth …